Mouse hairy and enhancer of split 6 (Drosophila) ELISA Kit | HES6 elisa kit
Mouse Transcription cofactor HES-6, HES6 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
HES6: Does not bind DNA itself but suppresses both HES1- mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription, coactivator/corepressor
Cellular Component: transcription factor complex; nucleus
Molecular Function: protein dimerization activity; DNA binding; transcription cofactor activity; transcription factor binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; nervous system development; regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter; cell differentiation
Research Articles on HES6
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Product Notes
The Mouse HES6 hes6 (Catalog #AAA9328144) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9328144 ELISA Kit recognizes Mouse HES6. It is sometimes possible for the material contained within the vial of "hairy and enhancer of split 6 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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