Lymphoid-specific helicase (HELLS) Recombinant Protein | HELLS recombinant protein

Recombinant Human Lymphoid-specific helicase (HELLS) , partial

• Gene Names: HELLS; LSH; ICF4; PASG; SMARCA6; Nbla10143
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Lymphoid-specific helicase (HELLS); Recombinant Human Lymphoid-specific helicase (HELLS); partial; HELLS recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 129

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for HELLS recombinant protein

This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

NCBI and Uniprot Product Information

• NCBI GI #: 574275033
• NCBI GeneID: 3070
• NCBI Accession #: NP_001275996.1
• NCBI GenBank Nucleotide #: NM_001289067.1
• UniProt Accession #: Q9NRZ9; Q3LID1; Q6I7N7; Q76H76; Q76H77; Q76H78; Q76H79; Q76H80; Q76H81; Q7Z397; Q7Z5X2; B2RB41
• Molecular Weight: 14,838 Da
• NCBI Official Full Name: lymphoid-specific helicase isoform 2
• NCBI Official Synonym Full Names: helicase, lymphoid specific
• NCBI Official Symbol: HELLS
• NCBI Official Synonym Symbols: LSH; ICF4; PASG; SMARCA6; Nbla10143
• NCBI Protein Information: lymphoid-specific helicase
• UniProt Protein Name: Lymphoid-specific helicase
• Protein Family: Lymphoid-specific helicase
• UniProt Gene Name: HELLS

NCBI Description

This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2014]

Uniprot Description

Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis ().