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EndoNEDD4 / NEDL2 Blocking Peptide | HECW2 blocking peptide

EndoNEDD4 / NEDL2 Immunizing Peptide

Gene Names
HECW2; NEDL2
Reactivity
Human, Mouse, Rat, Cow
Synonyms
EndoNEDD4 / NEDL2; EndoNEDD4 / NEDL2 Immunizing Peptide; HECW2; HECT; C2 and WW domain containing E3 ubiquitin protein ligase 2; NEDD4-related E3 ubiquitin ligase NEDL2; KIAA1301 protein; EndoNEDD4; DKFZp686M17164; NEDL2; HECW2 blocking peptide
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat, Cow
Form/Format
100ug of dried peptide
Sequence
ASSAREHLLFVRR-C
Sequence Length
1572
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
135,905 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase HECW2 isoform 1
NCBI Official Synonym Full Names
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
NCBI Official Symbol
HECW2
NCBI Official Synonym Symbols
NEDL2
NCBI Protein Information
E3 ubiquitin-protein ligase HECW2
UniProt Protein Name
E3 ubiquitin-protein ligase HECW2
UniProt Gene Name
HECW2
UniProt Synonym Gene Names
KIAA1301; NEDL2
UniProt Entry Name
HECW2_HUMAN

Uniprot Description

HECW2: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.2.-; Ubiquitin ligase; Ubiquitin conjugating system; Ligase; EC 6.3.2.19

Chromosomal Location of Human Ortholog: 2q32.3

Cellular Component: cytoplasm; nucleus

Molecular Function: ligase activity; ubiquitin-protein ligase activity

Biological Process: protein ubiquitination during ubiquitin-dependent protein catabolic process

Research Articles on HECW2

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Product Notes

The HECW2 hecw2 (Catalog #AAA426144) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The EndoNEDD4 / NEDL2 Immunizing Peptide reacts with Human, Mouse, Rat, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: ASSAREHLLF VRR-C. It is sometimes possible for the material contained within the vial of "EndoNEDD4 / NEDL2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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