Rat Histone deacetylase 8 ELISA Kit | Hdac8 elisa kit
Rat Histone deacetylase 8 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
HDAC8: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility. Belongs to the histone deacetylase family. HD type 1 subfamily. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.5.1.98; Hydrolase
Cellular Component: cytoplasm; nucleus; plasma membrane
Molecular Function: Hsp70 protein binding; Hsp90 protein binding; metal ion binding; NAD-dependent histone deacetylase activity (H3-K14 specific)
Biological Process: negative regulation of protein ubiquitination; regulation of protein stability; regulation of telomere maintenance; regulation of transcription, DNA-dependent; sister chromatid cohesion; transcription, DNA-dependent
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Product Notes
The Rat Hdac8 hdac8 (Catalog #AAA2885286) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2885286 ELISA Kit recognizes Rat Hdac8. It is sometimes possible for the material contained within the vial of "Histone deacetylase 8, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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