Hepatitis C Virus 4th Generation Recombinant Protein | HCV recombinant protein
Recombinant Hepatitis C Virus 4th Generation
Purity
Protein is >95% pure as determined by 12% PAGE (coomassie staining).Purified by proprietary chromatographic technique.
Synonyms
Hepatitis C Virus 4th Generation; Recombinant Hepatitis C Virus 4th Generation; HCV 4th Generation; Hepatitis C Virus 4th Generation Recombinant; HCV recombinant protein
Host
E Coli
Purity/Purification
Protein is >95% pure as determined by 12% PAGE (coomassie staining).
Purified by proprietary chromatographic technique.
Purified by proprietary chromatographic technique.
Form/Format
50mM PBS.
Sequence Length
3033
Application Notes
Each laboratory should determine an optimum working titer for use in its particular application.
Preparation and Storage
HCV 4th Generation although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.
Related Product Information for HCV recombinant protein
Description: The E Coli derived recombinant protein contains a HCV fourth generation antigen, containing medium size core NS3, 3 & 2 epitopes from NS4 and NS5, respectively. The genotype of all sequences is 1b. The recombinant protein migrates at 33kDa. This fourth generation HCV antigen is suitable to produce HCV lateral flow immunoassay product tested by whole blood, serum and plasma. The peptides from four regions, core, NS3, NS4, NS5 are fused together. Add 70ul-80ul whole blood, serum or plasma, due to high volume antibody sample, this medium size antigen is used.
Introduction: HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Introduction: HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Product Categories/Family for HCV recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
330,337 Da
NCBI Official Full Name
hepatitis C virus polyprotein
UniProt Protein Name
Genome polyprotein
UniProt Gene Name
HCV
UniProt Entry Name
D5MTP0_9HEPC
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Product Notes
The HCV hcv (Catalog #AAA142554) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. Each laboratory should determine an optimum working titer for use in its particular application. Researchers should empirically determine the suitability of the HCV hcv for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Hepatitis C Virus 4th Generation, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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