HBcAg recombinant protein
HBcAg Protein
Applications
ELISA
Purity
>90% by SDS-PAGE
Synonyms
HBcAg; HBcAg Protein; Capsid protein; Core antigen; Core protein; Hepatitis B core antigen; p21.5; Hepatitis BcAg; HBcAg recombinant protein
Host
E. coli
Purity/Purification
>90% by SDS-PAGE
Form/Format
Liquid; Each vial contains 0.02 M sodium phosphate (pH7.2) without preservative.
Concentration
2.6 mg/ml (varies by lot)
Applicable Applications for HBcAg recombinant protein
ELISA (EIA)
Application Notes
Other applications have not been tested. The optimal dilutions should be determined by the end user.
Inactivation
Heated for 10 hours at 60°C before ultracentrifugation.
Preparation and Storage
Ships on blue ice. Upon receipt, aliquot and store at -20°C or -80°Cfor long term. Avoid repeated freeze and thaw cycles.
Related Product Information for HBcAg recombinant protein
Description: Recombinant full length human Hepatitis BcAg protein.
Background: HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious). Hepatitis B virus (HBV) core antigen (HBcAg)-specific CD4(+) T-cell responses are believed to play an important role in the control of human HBV infection. HBcAg-specific CD4(+) Th1-type T cells can modulate the function and exert a regulatory role in deleting HBcAg-binding, or -specific, human B cells in vivo, which may be of importance in controlling the infection
Background: HBcAg (core antigen) is a hepatitis B viral protein. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious). Hepatitis B virus (HBV) core antigen (HBcAg)-specific CD4(+) T-cell responses are believed to play an important role in the control of human HBV infection. HBcAg-specific CD4(+) Th1-type T cells can modulate the function and exert a regulatory role in deleting HBcAg-binding, or -specific, human B cells in vivo, which may be of importance in controlling the infection
References
1. Kimura T, Rokuhara A, Matsumoto A, et al. (May 2003). "New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and relation between levels of HBcAg and HBV DNA". J. Clin. Microbiol. 41 (5): 1901-6. 2. Cao T, Meuleman P, Desombere I, Sällberg M, Leroux-Roels G (December 2001). "In vivo inhibition of anti-hepatitis B virus core antigen (HBcAg) immunoglobulin G production by HBcAg-specific CD4(+) Th1-type T-cell clones in a hu-PBL-NOD/SCID mouse model". J. Virol. 75 (23): 11449-56.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
HBcAg, partial
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Product Notes
The HBcAg (Catalog #AAA355629) is a Recombinant Protein produced from E. coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's HBcAg can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Other applications have not been tested. The optimal dilutions should be determined by the end user. Researchers should empirically determine the suitability of the HBcAg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HBcAg, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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