Hamster Sorcin (SRI) ELISA Kit | SRI elisa kit
Hamster Sorcin (SRI) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene. [provided by RefSeq, Mar 2012]
Uniprot Description
SRI: Calcium-binding protein that modulates excitation- contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
Protein type: Calcium-binding
Chromosomal Location of Human Ortholog: 7q21.1
Cellular Component: cytoplasm; cytosol; endoplasmic reticulum membrane; membrane; mitochondrion; nerve terminal; nucleoplasm; sarcoplasmic reticulum; sarcoplasmic reticulum membrane; smooth endoplasmic reticulum; T-tubule; Z disc
Molecular Function: calcium channel regulator activity; calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; identical protein binding; protease binding; protein binding; protein heterodimerization activity; receptor binding
Biological Process: calcium ion transport; cytoplasmic sequestering of transcription factor; heart development; intracellular sequestering of iron ion; muscle development; negative regulation of heart rate; positive regulation of release of sequestered calcium ion into cytosol; proteolysis; regulation of action potential; regulation of calcium ion transport; regulation of heart contraction; regulation of striated muscle contraction; signal transduction; transport
Research Articles on SRI
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Product Notes
The Hamster SRI sri (Catalog #AAA9360142) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9360142 ELISA Kit recognizes Hamster SRI. It is sometimes possible for the material contained within the vial of "Sorcin (SRI), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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