Hamster Nogo-B (NOGO-B) ELISA Kit | NOGO-B elisa kit
Hamster Nogo-B (NOGO-B) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Nogo: Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Cell development/differentiation; Endoplasmic reticulum; Inhibitor; Motility/polarity/chemotaxis; Membrane protein, integral
Cellular Component: cell projection; cell soma; cytoplasm; endoplasmic reticulum; integral to endoplasmic reticulum membrane; integral to membrane; intracellular; membrane; myelin sheath; neuron projection; nuclear envelope; plasma membrane; protein complex
Molecular Function: protein binding; protein complex binding
Biological Process: angiogenesis; axonal fasciculation; axonogenesis; cerebral cortex radial glia guided migration; negative regulation of axon extension; negative regulation of axonogenesis; negative regulation of cell growth; negative regulation of neuron differentiation; nervous system development; positive regulation of dopamine secretion; positive regulation of glial cell differentiation; regulation of cell migration; regulation of nervous system development; regulation of sensory perception of pain
Research Articles on NOGO-B
Similar Products
Product Notes
The Hamster NOGO-B rtn4 (Catalog #AAA9368149) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9368149 ELISA Kit recognizes Hamster NOGO-B. It is sometimes possible for the material contained within the vial of "Nogo-B (NOGO-B), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
