Human Hyaluronidase ELISA Kit | HAASE elisa kit

Human Hyaluronidase ELISA Kit

Cat. Num. AAA10472

• Gene Names: HYAL3; LUCA3; HYAL-3; LUCA-3
• Reactivity: Human
• Synonyms: Hyaluronidase; Human Hyaluronidase ELISA Kit; HAASE elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Serum, Plasma and Tissue Homogenate
• Detection Range: 15.6 ng/ml - 500 ng/ml.
• Sensitivity: 2.0 ng/ml.
• Assay Type: Sandwich
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for HAASE elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of HAASE (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

NCBI and Uniprot Product Information

• NCBI GI #: 2935328
• NCBI GeneID: 8372
• UniProt Accession #: O43820; O60540; Q8NFK2; Q8NFK3; Q8NFK4; Q96E56; Q9BRW9
• Molecular Weight: 46,501 Da
• NCBI Official Full Name: hyaluronidase
• NCBI Official Synonym Full Names: hyaluronoglucosaminidase 3
• NCBI Official Symbol: HYAL3
• NCBI Official Synonym Symbols: LUCA3; HYAL-3; LUCA-3
• NCBI Protein Information: hyaluronidase-3; lung carcinoma protein 3
• UniProt Protein Name: Hyaluronidase-3
• Protein Family: Hyaluronidase
• UniProt Gene Name: HYAL3
• UniProt Synonym Gene Names: LUCA3; Hyal-3; LuCa-3
• UniProt Entry Name: HYAL3_HUMAN

NCBI Description

This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]

Uniprot Description

HYAL3: a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]

Protein type: Secreted, signal peptide; EC 3.2.1.35; Secreted; Hydrolase

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: lysosome; extracellular region; cytoplasmic vesicle

Molecular Function: viral receptor activity; hyaluronoglucuronidase activity; hyalurononglucosaminidase activity

Biological Process: response to antibiotic; cartilage development; response to virus; carbohydrate metabolic process; inflammatory response; hyaluronan catabolic process