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Glycophorin-B Recombinant Protein | GYPB recombinant protein

Glycophorin-B

Gene Names
GYPB; SS; GPB; GYP; MNS; PAS-3; CD235b
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Glycophorin-B; GYPB recombinant protein
Ordering
For Research Use Only!
Host
Cell Free Expression
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Liquid containing glycerol
Sequence Positions
20-91. Full Length of Mature Protein
Sequence
LSTTEVAMHTSTSSSVTKSYISSQTNGETGQLVHRFTVPAPVVIILIILCVMAGIIGTILLISYSIRRLIKA
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Related Product Information for GYPB recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
Product Categories/Family for GYPB recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
6,352 Da
NCBI Official Full Name
glycophorin-B isoform 2
NCBI Official Synonym Full Names
glycophorin B (MNS blood group)
NCBI Official Symbol
GYPB
NCBI Official Synonym Symbols
SS; GPB; GYP; MNS; PAS-3; CD235b
NCBI Protein Information
glycophorin-B
UniProt Protein Name
Glycophorin-B
Protein Family
UniProt Gene Name
GYPB
UniProt Synonym Gene Names
GPB
UniProt Entry Name
GLPB_HUMAN

NCBI Description

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Uniprot Description

GYPB: This protein is a minor sialoglycoprotein in erythrocyte membranes. Belongs to the glycophorin-A family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q31.21

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: protein binding

Disease: Malaria, Susceptibility To

Research Articles on GYPB

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Product Notes

The GYPB gypb (Catalog #AAA7042838) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 20-91. Full Length of Mature Protein. The amino acid sequence is listed below: LSTTEVAMHT STSSSVTKSY ISSQTNGETG QLVHRFTVPA PVVIILIILC VMAGIIGTIL LISYSIRRLI KA. It is sometimes possible for the material contained within the vial of "Glycophorin-B, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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