Guinea Pig Visual system homeobox 2 (VSX2) ELISA Kit | VSX2 elisa kit
Guinea pig Visual system homeobox 2 (VSX2) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities. [provided by RefSeq, Oct 2009]
Uniprot Description
CHX10: Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells. Defects in VSX2 are the cause of microphthalmia isolated type 2 (MCOP2); also known as isolated clinical anophthalmia. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataractand other abnormalities like cataract may also be present. Defects in VSX2 are the cause of microphthalmia with cataracts and iris abnormalities (MCOPCTI). Defects in VSX2 are the cause of microphthalmia isolated with coloboma type 3 (MCOPCB3); also known as isolated colobomatous microphthalmia 3. Ocular colobomas are a set of malformations resulting from abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure). Belongs to the paired homeobox family.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 14q24.3
Cellular Component: cytoplasm; nucleus
Molecular Function: sequence-specific DNA binding
Biological Process: negative regulation of cell proliferation; cell fate commitment; visual perception; transcription, DNA-dependent; positive regulation of cell proliferation; response to stimulus; positive regulation of transcription from RNA polymerase II promoter; retinal bipolar neuron differentiation
Disease: Microphthalmia, Isolated 2; Microphthalmia, Isolated, With Coloboma 3
Research Articles on VSX2
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Product Notes
The Guinea Pig VSX2 vsx2 (Catalog #AAA7249630) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7249630 ELISA Kit recognizes Guinea Pig VSX2. It is sometimes possible for the material contained within the vial of "Visual system homeobox 2 (VSX2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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