Guinea Pig Cyclin-dependent kinase 11B (CDC2L1) ELISA Kit | CDC2L1 elisa kit
Guinea pig Cyclin-dependent kinase 11B (CDC2L1) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
CDK11B: a protein kinase of the CDK family. May act as a negative regulator of the normal cell cycle progression. Nine alternatively spliced isoforms have been described. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform is specifically induced in G2/M phase of the cell cycle. 2 isoforms, SV9 and 7, are produced by alternative initiation at Met-1 and Met-357 resulting in p110 and p58 isoforms, respectively. Deleted or altered frequently in neuroblastoma with amplified MYCN genes. Can be cleaved by caspases and demonstrated to play a role in cell apoptosis.
Protein type: Protein kinase, CMGC; EC 2.7.11.22; Motility/polarity/chemotaxis; Cell cycle regulation; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Apoptosis; CMGC group; CDK family; PITSLRE subfamily; CDK/PITSLRE subfamily
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: transferase activity; protein serine/threonine kinase activity; cyclin-dependent protein kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity
Biological Process: blastocyst development; regulation of mitosis; cell cycle; protein amino acid phosphorylation; phosphorylation; regulation of mRNA processing
Research Articles on CDC2L1
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Product Notes
The Guinea Pig CDC2L1 cdk11b (Catalog #AAA7215487) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7215487 ELISA Kit recognizes Guinea Pig CDC2L1. It is sometimes possible for the material contained within the vial of "Cyclin-dependent kinase 11B (CDC2L1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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