Guinea Pig Centrosomal protein of 63 kDa (CEP63) ELISA Kit | Cep63 elisa kit
Guinea pig Centrosomal protein of 63 kDa (CEP63) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a subunit of the centrosome, the main microtubule-organizing center of the cell. The encoded protein associates with another centrosomal protein, CEP152, to regulate mother-centriole-dependent centriole duplication in dividing cells. Disruption of a similar gene in human has been associated with primary microcephaly (MCPH). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Uniprot Description
CEP63: Required for normal spindle assembly. Maintains centrosome numbers through centrosomal recruitment of CEP152. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression. Defects in CEP63 are the cause of Seckel syndrome type 6 (SCKL6). A rare autosomal recessive disorder characterized by proportionate dwarfism of prenatal onset associated with low birth weight, growth retardation, severe microcephaly with a bird-headed like appearance, and mental retardation. Belongs to the CEP63 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Cellular Component: centriole; centrosome; cytoskeleton; cytoplasm
Molecular Function: protein binding
Biological Process: mitosis; cell division; centriole replication; cell cycle; response to DNA damage stimulus
Research Articles on Cep63
Similar Products
Product Notes
The Guinea Pig Cep63 cep63 (Catalog #AAA7202907) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7202907 ELISA Kit recognizes Guinea Pig Cep63. It is sometimes possible for the material contained within the vial of "Centrosomal protein of 63 kDa (CEP63), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
