Guinea Pig CCR4-NOT transcription complex subunit 7 (CNOT7) ELISA Kit | CNOT7 elisa kit
Guinea pig CCR4-NOT transcription complex subunit 7 (CNOT7) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]
Uniprot Description
CNOT7: Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression. Belongs to the CAF1 family.
Protein type: Transcription, coactivator/corepressor; EC 3.1.13.4
Chromosomal Location of Human Ortholog: 8p22-p21.3
Cellular Component: membrane; nucleus; cytosol; CCR4-NOT complex
Molecular Function: signal transducer activity; 3'-5'-exoribonuclease activity; protein binding; poly(A)-specific ribonuclease activity; exoribonuclease activity; RNA binding; metal ion binding; transcription factor activity
Biological Process: deadenylation-dependent decapping; transcription, DNA-dependent; miRNA-mediated gene silencing; signal transduction; regulation of translation; negative regulation of cell proliferation; poly(A) tail shortening; carbohydrate metabolic process; positive regulation of cell proliferation; gene expression; cytoplasmic mRNA processing body assembly; positive regulation of transcription from RNA polymerase II promoter; RNA-mediated gene silencing; mRNA catabolic process, deadenylation-dependent decay
Research Articles on CNOT7
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Product Notes
The Guinea Pig CNOT7 cnot7 (Catalog #AAA7237328) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7237328 ELISA Kit recognizes Guinea Pig CNOT7. It is sometimes possible for the material contained within the vial of "CCR4-NOT transcription complex subunit 7 (CNOT7), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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