Guinea Pig Angiogenic factor with G patch and FHA domains 1 (AGGF1) ELISA Kit | AGGF1 elisa kit
Guinea pig Angiogenic factor with G patch and FHA domains 1 (AGGF1) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010]
Uniprot Description
AGGF1: Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. Defects in AGGF1 are a cause of Klippel-Trenaunay syndrome (KTS). KTS is a congenital disease characterized by malformations of capillary (98% of KTS patients), venous (72%) and lymphatic (11%) vessels, and bony and soft tissue hypertrophy that leads to large cutaneous hemangiomata with hypertrophy of the related bones and soft tissues. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; RNA processing
Chromosomal Location of Human Ortholog: 5q13.3
Cellular Component: perinuclear region of cytoplasm; cytoplasm; extracellular region
Molecular Function: protein binding; nucleic acid binding
Biological Process: RNA processing; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; angiogenesis; vasculogenesis; cell adhesion
Disease: Klippel-trenaunay-weber Syndrome
Research Articles on AGGF1
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Product Notes
The Guinea Pig AGGF1 aggf1 (Catalog #AAA7210406) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7210406 ELISA Kit recognizes Guinea Pig AGGF1. It is sometimes possible for the material contained within the vial of "Angiogenic factor with G patch and FHA domains 1 (AGGF1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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