Guinea Pig Amino-terminal enhancer of split (AES) ELISA Kit | AES elisa kit
Guinea pig Amino-terminal enhancer of split (AES) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
AES: Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Belongs to the WD repeat Groucho/TLE family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: nucleus
Molecular Function: protein binding; transcription corepressor activity
Biological Process: organ morphogenesis; Wnt receptor signaling pathway; transcription, DNA-dependent; multicellular organismal development; regulation of growth; cellular response to extracellular stimulus; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of protein binding; skeletal development
Research Articles on AES
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Product Notes
The Guinea Pig AES aes (Catalog #AAA7236068) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7236068 ELISA Kit recognizes Guinea Pig AES. It is sometimes possible for the material contained within the vial of "Amino-terminal enhancer of split (AES), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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