Guinea Pig Age-related maculopathy susceptibility protein 2 (ARMS2) ELISA Kit | ARMS2 elisa kit
Guinea pig Age-related maculopathy susceptibility protein 2 (ARMS2) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is thought to play a role in diseases in the elderly. Mutations in this gene have been associated with age-related macular degeneration. [provided by RefSeq, Oct 2008]
Uniprot Description
ARMS2: Defects in ARMS2 influence susceptibility to age-related macular degeneration type 8 (ARMD8). ARMD is the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid (known as drusen) that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch's membrane. ARMD is likely to be a mechanistically heterogeneous group of disorders, and the specific disease mechanisms that underlie the vast majority of cases are currently unknown. However, a number of studies have suggested that both genetic and environmental factors are likely to play a role.
Chromosomal Location of Human Ortholog: 10q26.13
Cellular Component: photoreceptor inner segment; mitochondrion
Biological Process: retinal homeostasis
Disease: Macular Degeneration, Age-related, 8
Research Articles on ARMS2
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Product Notes
The Guinea Pig ARMS2 arms2 (Catalog #AAA7208193) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7208193 ELISA Kit recognizes Guinea Pig ARMS2. It is sometimes possible for the material contained within the vial of "Age-related maculopathy susceptibility protein 2 (ARMS2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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