Guinea Pig ADP-ribosylation factor-like protein 2-binding protein (ARL2BP) ELISA Kit | ARL2BP elisa kit
Guinea pig ADP-ribosylation factor-like protein 2-binding protein (ARL2BP) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]
Uniprot Description
ARL2BP: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. Belongs to the ARL2BP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein regulator, misc.; Mitochondrial
Chromosomal Location of Human Ortholog: 16q13
Cellular Component: centrosome; mitochondrial intermembrane space; spindle; midbody; nucleus; cilium
Molecular Function: protein binding; transcription coactivator activity
Biological Process: regulation of catalytic activity; maintenance of protein localization in nucleus; signal transduction; positive regulation of tyrosine phosphorylation of Stat3 protein
Disease: Retinitis Pigmentosa With Or Without Situs Inversus
Research Articles on ARL2BP
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Product Notes
The Guinea Pig ARL2BP arl2bp (Catalog #AAA7234697) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA7234697 ELISA Kit recognizes Guinea Pig ARL2BP. It is sometimes possible for the material contained within the vial of "ADP-ribosylation factor-like protein 2-binding protein (ARL2BP), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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