Retinal guanylyl cyclase 1 (GUCY2D) Recombinant Protein | GUCY2D recombinant protein
Recombinant Bovine Retinal guanylyl cyclase 1 (GUCY2D), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Retinal guanylyl cyclase 1 (GUCY2D); Recombinant Bovine Retinal guanylyl cyclase 1 (GUCY2D); partial; GUCY2D recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
57-467
Sequence
AVFT VGVLGPWACD PIFARARPDL AARLAASRLN HAAALEGGPR FEVALLPEPC RTPGSLGAVS SALTRVSGLV GPVNPAACRP AELLAQEAGV ALVPWGCPGT RAAGTTAPVV TPAADALYAL LRAFRWAHVA LVTAPQDLWV EAGHALSTAL RARGLPVALV TSMEPSDLSG AREALRRVQD GPRVRAVIMV MHSVLLGGEE QRCLLEAAEE LGLADGSLVF LPFDTLHYAL SPGPDALAVL ANSSQLRKAH DAVLTLTRHC PLGGSVRDSL RRAQEHRELP LDLNLQQVSP LFGTIYDSVF LLAGGVARAR VAAGGGWVSG AAVARHIRDA RVPGFCGALG GAEEPSFVLL DTDATGDQLF ATYVLDPTQG FFHSAGTPVH FPKGGRGPGP DPSCWFDPDT ICNGGVE
Sequence Length
411
Species
Bovine
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for GUCY2D recombinant protein
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
120,369 Da
NCBI Official Full Name
Retinal guanylyl cyclase 1
NCBI Official Synonym Full Names
guanylate cyclase 2D, retinal
NCBI Official Symbol
GUCY2D
NCBI Protein Information
retinal guanylyl cyclase 1
UniProt Protein Name
Retinal guanylyl cyclase 1
Protein Family
UniProt Gene Name
GUCY2D
UniProt Synonym Gene Names
GUC2D; RETGC-1; GC-E; ROS-GC
Uniprot Description
Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
Research Articles on GUCY2D
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Product Notes
The GUCY2D gucy2d (Catalog #AAA953402) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 57-467. The amino acid sequence is listed below: AVFT VGVLGPWACD PIFARARPDL AARLAASRLN HAAALEGGPR FEVALLPEPC RTPGSLGAVS SALTRVSGLV GPVNPAACRP AELLAQEAGV ALVPWGCPGT RAAGTTAPVV TPAADALYAL LRAFRWAHVA LVTAPQDLWV EAGHALSTAL RARGLPVALV TSMEPSDLSG AREALRRVQD GPRVRAVIMV MHSVLLGGEE QRCLLEAAEE LGLADGSLVF LPFDTLHYAL SPGPDALAVL ANSSQLRKAH DAVLTLTRHC PLGGSVRDSL RRAQEHRELP LDLNLQQVSP LFGTIYDSVF LLAGGVARAR VAAGGGWVSG AAVARHIRDA RVPGFCGALG GAEEPSFVLL DTDATGDQLF ATYVLDPTQG FFHSAGTPVH FPKGGRGPGP DPSCWFDPDT ICNGGVE. It is sometimes possible for the material contained within the vial of "Retinal guanylyl cyclase 1 (GUCY2D), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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