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SDS-Page (Figure 1. Human GUCY2C Protein, His Tag on SDS-PAGE under reducing condition.)

GUCY2C recombinant protein

Human GUCY2C Protein, His Tag

Gene Names
GUCY2C; STAR; DIAR6; GUC2C; MECIL; MUCIL
Purity
>95%; affinity purification
Synonyms
GUCY2C; Human GUCY2C Protein; His Tag; DIAR6; GC-C; GUC2C; MECIL; MUCIL; STAR; GUCY2C recombinant protein
Ordering
For Research Use Only!
Host
HEK293 cells
Purity/Purification
>95%; affinity purification
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose is added as protectants before lyophilization.
Sequence
GUCY2C (Ser24-Gln430)+6×His tag
Species
Human
Tag
C-6×His tag
Reconstitution
Reconstitute with deionized water
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)

SDS-Page

(Figure 1. Human GUCY2C Protein, His Tag on SDS-PAGE under reducing condition.)

SDS-Page (Figure 1. Human GUCY2C Protein, His Tag on SDS-PAGE under reducing condition.)
Related Product Information for GUCY2C recombinant protein
This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
123,403 Da
NCBI Official Full Name
heat-stable enterotoxin receptor
NCBI Official Synonym Full Names
guanylate cyclase 2C
NCBI Official Symbol
GUCY2C
NCBI Official Synonym Symbols
STAR; DIAR6; GUC2C; MECIL; MUCIL
NCBI Protein Information
heat-stable enterotoxin receptor
UniProt Protein Name
Heat-stable enterotoxin receptor
UniProt Gene Name
GUCY2C
UniProt Synonym Gene Names
GUC2C; STAR; STA receptor; hSTAR; GC-C

Uniprot Description

Receptor for the E.coli heat-stable enterotoxin (E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GC-C). Also activated by the endogenous peptides guanylin and uroguanylin.

Research Articles on GUCY2C

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Product Notes

The GUCY2C gucy2c (Catalog #AAA188789) is a Recombinant Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: GUCY2C (Ser24-Gln 430)+6×Hi s tag. It is sometimes possible for the material contained within the vial of "GUCY2C, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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