Guanylyl Cyclase alpha 2 Blocking Peptide | GUCY1A2 blocking peptide

Guanylyl Cyclase alpha 2 Blocking Peptide

Gene Names

GUCY1A2; GC-SA2; GUC1A2

Applications

Blocking/Control

Purity

The purity is >90%,tested by HPLC and MS.

Synonyms

Guanylyl Cyclase alpha 2; Guanylyl Cyclase alpha 2 Blocking Peptide; GC SA2; GCS alpha 2; GCS-alpha-2; GCYA2_HUMAN; Guanylate cyclase soluble subunit alpha-2; GUC1A2; GUCSA2; GUCY1A2; GUCY1A2 blocking peptide

Ordering
Cat. Num. AAA9622250 For Research Use Only!

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Applicable Applications for GUCY1A2 blocking peptide

Blocking/Control

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for GUCY1A2 blocking peptide

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. This mechanism is useful when non-specific binding is an issue, for example, in Western blotting (immunoblot) and immunohistochemistry (IHC). By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific; Specific binding will be absent from the western blot or immunostaining performed with the neutralized antibody.

NCBI and Uniprot Product Information

NCBI GI #

4504211

NCBI GeneID

2977

NCBI Accession #

NP_000846.1

NCBI GenBank Nucleotide #

NP_000846.1

UniProt Accession #

P33402; A1L4C4

Molecular Weight

81,750 Da

NCBI Official Full Name

guanylate cyclase soluble subunit alpha-2

NCBI Official Synonym Full Names

guanylate cyclase 1, soluble, alpha 2

NCBI Official Symbol

GUCY1A2

NCBI Official Synonym Symbols

GC-SA2; GUC1A2

NCBI Protein Information

guanylate cyclase soluble subunit alpha-2; GCS-alpha-2; OTTHUMP00000232532; OTTHUMP00000232533; OTTHUMP00000232534

UniProt Protein Name

Guanylate cyclase soluble subunit alpha-2

Protein Family

Guanylate cyclase soluble

UniProt Gene Name

GUCY1A2

UniProt Synonym Gene Names

GUC1A2; GUCSA2

UniProt Entry Name

GCYA2_HUMAN

NCBI Description

Soluble guanylyl (or guanylate) cyclases are heterodimeric enzymes consisting of an alpha subunit, such as alpha-2 (GUCY1A2), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), which are activated by nitric oxide (NO) and which catalyze conversion of GTP to 3-prime, 5-prime-cyclic GMP and pyrophosphate (Harteneck et al., 1991 [PubMed 1683630]).[supplied by OMIM]

Uniprot Description

GUCY1A2: Has guanylyl cyclase on binding to the beta-1 subunit. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lyase; Nucleotide Metabolism - purine; EC 4.6.1.2; Guanylyl cyclase

Chromosomal Location of Human Ortholog: 11q21-q22

Cellular Component: cytoplasm

Molecular Function: guanylate cyclase activity; GTP binding; heme binding

Biological Process: cGMP biosynthetic process; positive regulation of cGMP biosynthetic process; blood coagulation; signal transduction

Research Articles on GUCY1A2

1. Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)

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Product Notes

The GUCY1A2 gucy1a2 (Catalog #AAA9622250) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Guanylyl Cyclase alpha 2 can be used in a range of immunoassay formats including, but not limited to, Blocking/Control. Researchers should empirically determine the suitability of the GUCY1A2 gucy1a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Guanylyl Cyclase alpha 2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Guanylyl Cyclase alpha 2 Blocking Peptide | GUCY1A2 blocking peptide