SDS-Page
GSTZ1 recombinant protein
GSTZ1, 1-216aa, Human, His tag, E Coli
Gene Names
GSTZ1; MAI; MAAI; MAAID; GSTZ1-1
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
GSTZ1; 1-216aa; Human; His tag; E Coli; Glutathione S-transferase zeta 1; GSTZ1-1; MAAI; MAI; Glutathione S-transferase zeta 1 EC 2.5.1.18; EC 5.2.1.2; Glutathione S transferase zeta 1; Glutathione S-Transferase Zeta-1; GSTZ1 recombinant protein
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid. In phosphate buffered saline pH7.4 containing 10% glycerol
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MQAGKPILYS YFRSSCSWRV RIALALKGID YETVPINLIK DGGQQFSKDF QALNPMKQVP TLKIDGITIH QSLAIIEYLE ETRPTPRLLP QDPKKRASVR MISDLIAGGI QPLQNLSVLK QVGEEMQLTW AQNAITCGFN ALEQILQSTA GIYCVGDEVT MADLCLVPQV ANAERFKVDL TPYPTISSIN KRLLVLEAFQ VSHPCRQPDT PTELRA
Sequence Length
216
Applicable Applications for GSTZ1 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for GSTZ1 recombinant protein
GSTZ1, also known as maleylacetoacetate isomerase, is an enzyme that belongs to glutathione S-transferase (GSTs) super-family. This enzyme acts by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S=sulfur). The reactions utilizing glutathione contribute the transformation of a wide variety of electrophiles, including reactive products of lipid, protein, carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. It also plays a significant role in the catabolism of phenylalanine and tyrosine. Recombinant GSTZ1 protein was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for GSTZ1 recombinant protein
References
Board PG, et al. (1997) Biochem J. 328:929-35.; Fernandez-Canon JM., et al. (1998) J Biol Chem. 273 (1):329-37;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
26.2 kDa (236aa), confirmed by MALDI-TOF.
NCBI Official Full Name
glutathione transferase zeta 1
NCBI Official Synonym Full Names
glutathione S-transferase zeta 1
NCBI Official Symbol
GSTZ1
NCBI Official Synonym Symbols
MAI; MAAI; MAAID; GSTZ1-1
NCBI Protein Information
maleylacetoacetate isomerase
UniProt Protein Name
Maleylacetoacetate isomerase
Protein Family
UniProt Gene Name
GSTZ1
UniProt Synonym Gene Names
MAAI; MAAI
NCBI Description
This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme catalyzes the conversion of maleylacetoacetate to fumarylacetoacatate, which is one of the steps in the phenylalanine/tyrosine degradation pathway. Deficiency of a similar gene in mouse causes oxidative stress. Several transcript variants of this gene encode multiple protein isoforms. [provided by RefSeq, Jul 2015]
Uniprot Description
Bifunctional enzyme showing minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid.
Research Articles on GSTZ1
Similar Products
Product Notes
The GSTZ1 gstz1 (Catalog #AAA203407) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's GSTZ1 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the GSTZ1 gstz1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSH MQAGKPILYS YFRSSCSWRV RIALALKGID YETVPINLIK DGGQQFSKDF QALNPMKQVP TLKIDGITIH QSLAIIEYLE ETRPTPRLLP QDPKKRASVR MISDLIAGGI QPLQNLSVLK QVGEEMQLTW AQNAITCGFN ALEQILQSTA GIYCVGDEVT MADLCLVPQV ANAERFKVDL TPYPTISSIN KRLLVLEAFQ VSHPCRQPDT PTELRA. It is sometimes possible for the material contained within the vial of "GSTZ1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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