Human GSK3-beta interaction protein ELISA Kit | GSKIP elisa kit
Human GSK3-beta interaction protein ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]
Uniprot Description
GSKIP: Belongs to the UPF0279 family.
Chromosomal Location of Human Ortholog: 14q32.2
Research Articles on GSKIP
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Product Notes
The Human GSKIP gskip (Catalog #AAA2888093) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2888093 ELISA Kit recognizes Human GSKIP. It is sometimes possible for the material contained within the vial of "GSK3-beta interaction protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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