Rabbit anti-Human, Mouse NFkappaB-p105/p50 Polyclonal Antibody | anti-NFkappaB-p105/p50 antibody

NFkappaB-p105/p50 (Phospho-Ser337) Rabbit Polyclonal Antibody

Cat. Num. AAA318642

• Gene Names: NFKB1; p50; KBF1; p105; EBP-1; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B
• Reactivity: Human, Mouse
• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: NFkappaB-p105/p50, Antibody; NFkappaB-p105/p50 (Phospho-Ser337) Rabbit Polyclonal Antibody; NFkappaB1; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; BH6842; anti-NFkappaB-p105/p50 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: Phospho-NFkappaB-p105/p50 (S337) Polyclonal Antibody detects endogenous levels of NFkappaB-p105/p50 protein only when phosphorylated at S337.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Concentration: 1mg/ml (varies by lot)

• Applicable Applications for anti-NFkappaB-p105/p50 antibody: ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Synthesized phospho-peptide around the phosphorylation site of human NFkappaB-p105/p50 (phospho Ser337)
• Modification: Phospho Specific
• Preparation and Storage: Store at -20 degree C/1 year

WB (Western Blot)

(Western Blot analysis of various cells using Phospho-NF?B-p105/p50 (S337) Polyclonal Antibody diluted at 1:500)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4 degree overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.)

IHC (Immunohistochemisry)

(Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4 degree overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.)

IHC (Immunohiostchemistry)

(Immunohistochemistry analysis of paraffin-embedded human breast cancer, using NF-?B p105/p50 (Phospho-Ser337) Antibody. The picture on the right is blocked with the NF-?B p105/p50 (Phospho-Ser337) peptide.)

WB (Western Blot)

(Western blot analysis of NF-?B p105/p50 (Phospho-Ser337) Antibody. The lane on the right is blocked with the NF-?B p105/p50 (Phospho-Ser337) peptide.)

Related Product Information for anti-NFkappaB-p105/p50 antibody

nuclear factor kappa B subunit 1 (NFkappaB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFkappaB) Protein complex. NFkappaB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFkappaB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFkappaB has been associated with a number of inflammatory diseases while persistent inhibition of NFkappaB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isof

NCBI and Uniprot Product Information

• NCBI GI #: 259155302
• NCBI GeneID: 4790
• NCBI Accession #: NP_001158884.1
• NCBI GenBank Nucleotide #: NM_001165412.1
• UniProt Accession #: P19838; Q68D84; Q86V43; Q8N4X7; Q9NZC0; A8K5Y5; B3KVE8
• Molecular Weight: 105,356 Da
• NCBI Official Full Name: nuclear factor NF-kappa-B p105 subunit isoform 2
• NCBI Official Synonym Full Names: nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
• NCBI Official Symbol: NFKB1
• NCBI Official Synonym Symbols: p50; KBF1; p105; EBP-1; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B
• NCBI Protein Information: nuclear factor NF-kappa-B p105 subunit; NF-kappabeta; DNA binding factor KBF1; DNA-binding factor KBF1; nuclear factor NF-kappa-B p50 subunit; nuclear factor kappa-B DNA binding subunit
• UniProt Protein Name: Nuclear factor NF-kappa-B p105 subunit
• UniProt Gene Name: NFKB1
• UniProt Entry Name: NFKB1_HUMAN