Rat G protein-coupled receptor kinase 4 ELISA Kit | GRK4 elisa kit

Rat G protein-coupled receptor kinase 4, GRK4 ELISA Kit

Cat. Num. AAA9318544

• Gene Names: Grk4; Gprk2l
• Reactivity: Rat
• Synonyms: G protein-coupled receptor kinase 4; Rat G protein-coupled receptor kinase 4; GRK4 ELISA Kit; Rat G protein-coupled receptor kinase 4 (GRK4) ELISA kit; GPRK2L; GPRK4; GRK4a; IT11; G protein-coupled receptor kinase 2-like; G-protein coupled receptor kinase 4; GRK4 elisa kit

• Reactivity: Rat

• Samples: Rat Body Fluids And Tissue Homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 0.625ng/ml-20ng/ml
• Sensitivity: 0.1ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for GRK4 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of GRIN2B (hereafter termed "analyte") in undiluted original Rat body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 12621084
• NCBI GeneID: 59077
• NCBI Accession #: NP_075217.1
• NCBI GenBank Nucleotide #: NM_022928.1
• UniProt Accession #: P70507; P70508
• Molecular Weight: 66,788 Da
• NCBI Official Full Name: G protein-coupled receptor kinase 4
• NCBI Official Synonym Full Names: G protein-coupled receptor kinase 4
• NCBI Official Symbol: Grk4
• NCBI Official Synonym Symbols: Gprk2l
• NCBI Protein Information: G protein-coupled receptor kinase 4; g protein-coupled receptor kinase GRK4; G protein-coupled receptor kinase 2, groucho gene related
• UniProt Protein Name: G protein-coupled receptor kinase 4
• Protein Family: G protein-coupled receptor kinase
• UniProt Gene Name: Grk4
• UniProt Synonym Gene Names: Gprk2l
• UniProt Entry Name: GRK4_RAT

NCBI Description

kinase that phosphorylates agonist-occupied form of G protein-coupled receptors and may be involved in testicular and spermatocyte development [RGD, Feb 2006]

Uniprot Description

GRK4: Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, AGC; EC 2.7.11.16; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); AGC group; GRK family; GRK subfamily

Cellular Component: cell soma; dendrite; cell cortex; cytosol

Molecular Function: G-protein coupled receptor kinase activity; rhodopsin kinase activity; ATP binding

Biological Process: desensitization of G-protein coupled receptor protein signaling pathway; G-protein coupled receptor internalization; receptor internalization; signal transduction; protein amino acid phosphorylation