Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) Recombinant Protein | GPAA1 recombinant protein
Recombinant Human Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
NCBI Description
Posttranslational glycosylphosphatidylinositol (GPI) anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane. The protein encoded by this gene presumably functions in GPI anchoring at the GPI transfer step. The mRNA transcript is ubiquitously expressed in both fetal and adult tissues. The anchor attachment protein 1 contains an N-terminal signal sequence, 1 cAMP- and cGMP-dependent protein kinase phosphorylation site, 1 leucine zipper pattern, 2 potential N-glycosylation sites, and 8 putative transmembrane domains. [provided by RefSeq, Jul 2008]
Uniprot Description
GPAA1: Essential for GPI-anchoring of precursor proteins but not for GPI synthesis. Acts before or during formation of the carbonyl intermediate. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: endoplasmic reticulum membrane; GPI-anchor transamidase complex; membrane
Molecular Function: GPI-anchor transamidase activity; protein binding; tubulin binding
Biological Process: attachment of GPI anchor to protein; protein complex assembly; protein retention in ER
Research Articles on GPAA1
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Product Notes
The GPAA1 gpaa1 (Catalog #AAA7015978) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-621aa; Full Length of Mature Protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the GPAA1 gpaa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: GLLSDPVRRR ALARLVLRLN APLCVLSYVA GIAWFLALVF PPLTQRTYMS ENAMGSTMVE EQFAGGDRAR AFARDFAAHR KKSGALPVAW LERTMRSVGL EVYTQSFSRK LPFPDETHER YMVSGTNVYG ILRAPRAAST ESLVLTVPCG SDSTNSQAVG LLLALAAHFR GQIYWAKDIV FLVTEHDLLG TEAWLEAYHD VNVTGMQSSP LQGRAGAIQA AVALELSSDV VTSLDVAVEG LNGQLPNLDL LNLFQTFCQK GGLLCTLQGK LQPEDWTSLD GPLQGLQTLL LMVLRQASGR PHGSHGLFLR YRVEALTLRG INSFRQYKYD LVAVGKALEG MFRKLNHLLE RLHQSFFLYL LPGLSRFVSI GLYMPAVGFL LLVLGLKALE LWMQLHEAGM GLEEPGGAPG PSVPLPPSQG VGLASLVAPL LISQAMGLAL YVLPVLGQHV ATQHFPVAEA EAVVLTLLAI YAAGLALPHN THRVVSTQAP DRGWMALKLV ALIYLALQLG CIALTNFSLG FLLATTMVPT AALAKPHGPR TLYAALLVLT SPAATLLGSL FLWRELQEAP LSLAEGWQLF LAALAQGVLE HHTYGALLFP LLSLGLYPCW LLFWNVLFWK . It is sometimes possible for the material contained within the vial of "Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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