Goose PDZ Domain Containing 3 (PDZD3) ELISA Kit | PDZD3 elisa kit

Goose PDZ Domain Containing 3 (PDZD3) ELISA Kit

• Gene Names: PDZD3; IKEPP; PDZK2; NHERF4
• Reactivity: Goose
• Synonyms: PDZ Domain Containing 3 (PDZD3); Goose PDZ Domain Containing 3 (PDZD3) ELISA Kit; PDZD3 elisa kit

• Reactivity: Goose

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 20809634
• NCBI GeneID: 79849
• Molecular Weight: 54,217 Da
• NCBI Official Full Name: PDZ domain containing 3
• NCBI Official Synonym Full Names: PDZ domain containing 3
• NCBI Official Symbol: PDZD3
• NCBI Official Synonym Symbols: IKEPP; PDZK2; NHERF4
• NCBI Protein Information: Na(+)/H(+) exchange regulatory cofactor NHE-RF4
• UniProt Protein Name: Na(+)/H(+) exchange regulatory cofactor NHE-RF4
• Protein Family: Na(+)/H(+) exchange regulatory cofactor
• UniProt Gene Name: PDZD3
• UniProt Synonym Gene Names: IKEPP; NHERF4; PDZK2; NHERF-4; Na/Pi cotransporter C-terminal-associated protein 2; NaPi-Cap2

NCBI Description

Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).[supplied by OMIM, Mar 2008]

Uniprot Description

Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation (PubMed:11950846). Stimulates SLC9A3 activity in the presence of elevated calcium ions (PubMed:19088451).