IgG Fc Secondary Antibody | FCGR3B secondary antibody
Goat anti-Human IgG Fc, Affinity Pure, TRITC Conjugate, min x w/bovine, horse, mouse or rabbit serum proteins or mouse IgG1
Gene Names
FCGR3B; CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb
Reactivity
Human.Cross Reactivity: Based on IEP, no reactivity is observed to:
non-immunoglobulin human serum immunoglobulins
light chains on all human immunoglobulins
human IgG F(ab)2 fragment
serum proteins from bovine, horse, mouse, or rabbit
Applications
Flow Cytometry, Functional Assay, Immunofluorescence, ELISA
Purity
Affinity purified antibody is > 95% based on SDS-PAGEAffinity purified using solid phase Human IgG.
Synonyms
IgG Fc; Goat anti-Human IgG Fc; Affinity Pure; TRITC Conjugate; min x w/bovine; horse; mouse or rabbit serum proteins or mouse IgG1; Goat anti-Human IgG Fc - Affinity Pure; FCGR3B secondary antibody
Host
Goat
Reactivity
Human.
Cross Reactivity: Based on IEP, no reactivity is observed to:
non-immunoglobulin human serum immunoglobulins
light chains on all human immunoglobulins
human IgG F(ab)2 fragment
serum proteins from bovine, horse, mouse, or rabbit
Cross Reactivity: Based on IEP, no reactivity is observed to:
non-immunoglobulin human serum immunoglobulins
light chains on all human immunoglobulins
human IgG F(ab)2 fragment
serum proteins from bovine, horse, mouse, or rabbit
Specificity
Based on IEP, this antibody reacts with: heavy (gamma) chains on Human IgG
Purity/Purification
Affinity purified antibody is > 95% based on SDS-PAGE
Affinity purified using solid phase Human IgG.
Affinity purified using solid phase Human IgG.
Form/Format
Lyophilized
Concentration
1.0 mg/ml (E 1% at 280 nm = 13.0) (varies by lot)
Sequence Length
233
Applicable Applications for FCGR3B secondary antibody
Flow Cytometry (FC/FACS), Immunofluorescence (IF), ELISA (EIA), Immunomicroscopy (IM)
Conjugate
Tetramethylrhodamine-5-isothiocyanate (TRITC) Amax = 550 nm; Emax = 570 nm
Immunogen
Purified Human IgG, Fc fragment
Buffer
10 mM Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 1 % (w/v) BSA, Protease/IgG free
Preservative
0.05% (w/v) Sodium Azide
Reconstitution
Rehydrate with 1.1 ml of deionized water and let stand 30 minutes at room temperature to dissolve. Centrifuge to remove any particulates. Prepare fresh working dilution daily.
Country of Origin
Goat serum was obtained from healthy animals of US origin and under the care of a registered veterinarian.
Preparation and Storage
Store at 2-8 degree C.
Shelf Life: 1 year from date of receipt.
Prepare working dilution prior to use and then discard.
Shelf Life: 1 year from date of receipt.
Prepare working dilution prior to use and then discard.
Product Categories/Family for FCGR3B secondary antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,216 Da
NCBI Official Full Name
low affinity immunoglobulin gamma Fc region receptor III-B isoform 2
NCBI Official Synonym Full Names
Fc fragment of IgG receptor IIIb
NCBI Official Symbol
FCGR3B
NCBI Official Synonym Symbols
CD16; FCG3; CD16b; FCGR3; FCR-10; FCRIII; FCRIIIb
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor III-B
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor III-B
Protein Family
UniProt Gene Name
FCGR3B
UniProt Synonym Gene Names
CD16B; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb
NCBI Description
The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]
Uniprot Description
Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Research Articles on FCGR3B
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Product Notes
The FCGR3B fcgr3b (Catalog #AAA686086) is a Secondary Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Human IgG Fc, Affinity Pure, TRITC Conjugate, min x w/bovine, horse, mouse or rabbit serum proteins or mouse IgG1 reacts with Human. Cross Reactivity: Based on IEP, no reactivity is observed to: non-immunoglobulin human serum immunoglobulins light chains on all human immunoglobulins human IgG F(ab)2 fragment serum proteins from bovine, horse, mouse, or rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's IgG Fc can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunofluorescence (IF), ELISA (EIA), Immunomicroscopy (IM). Researchers should empirically determine the suitability of the FCGR3B fcgr3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IgG Fc, Secondary Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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