Guanine Nucleotide Binding Protein Beta Polypeptide 2-like 1 Recombinant Protein | GNB2L1 recombinant protein

Recombinant Human Guanine Nucleotide Binding Protein Beta Polypeptide 2-like 1

Cat. Num. AAA145212

• Gene Names: GNB2L1; H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1
• Purity: Greater than 95% as determined by SDS-PAGE.
• Synonyms: Guanine Nucleotide Binding Protein Beta Polypeptide 2-like 1; Recombinant Human Guanine Nucleotide Binding Protein Beta Polypeptide 2-like 1; GNB2L1 Human; Guanine Nucleotide Binding Protein beta polypeptide 2-like 1 Human Recombinant; Guanine nucleotide binding protein (G protein) beta polypeptide 2-like 1; RACK1; Receptor for Activated C Kinase 1; Gnb2-rs1; H12.3; Cell proliferation-inducing gene 21 protein; Guanine nucleotide-binding protein subunit beta-like protein 12.3; Human lung cancer oncogene 7 protein; Receptor of activated protein kinase C 1; HLC-7; PIG21; proliferation-inducing gene 21; protein homologous to chicken B complex protein guanine nucleotide binding; GNB2L1 recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 95% as determined by SDS-PAGE.
• Form/Format: The GNB2L1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 200mM NaCl, 5mM DTT and 50% glycerol.; Sterile Filtered colorless solution.
• Sequence: MGSSHHHHHH SSGLVPRGSH MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTI IMWKLTRDET NYGIPQRALR GHSHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI VSGSRDKTIK LWNTLGVCKY TVQDESHSEW VSCVRFSPNS SNPIIVSCGW DKLVKVWNLA NCKLKTNHIG HTGYLNTVTV SPDGSLCASG GKDGQAMLWD LNEGKHLYTL DGGDIINALC FSPNRYWLCA ATGPSIKIWD LEGKIIVDEL KQEVISTSSK AEPPQCTSLA WSADGQTLFA GYTDNLVRVW QVTIGTR
• Sequence Length: 317

Related Product Information for GNB2L1 recombinant protein

Description: GNB2L1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 337 amino acids (1-317 and having a molecular mass of 37.2kDa.GNB2L1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Product Categories/Family for GNB2L1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Guanine Nucleotide Binding Protein

NCBI and Uniprot Product Information

• NCBI GI #: 5174447
• NCBI GeneID: 10399
• NCBI Accession #: NP_006089.1
• NCBI GenBank Nucleotide #: NM_006098.4
• UniProt Accession #: P63244; P25388; P99049; Q53HU2; Q5J8M6; Q5VLR4; Q6FH47; B3KTJ0; D3DWS0
• Molecular Weight: 35,077 Da
• NCBI Official Full Name: guanine nucleotide-binding protein subunit beta-2-like 1
• NCBI Official Synonym Full Names: guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
• NCBI Official Symbol: GNB2L1
• NCBI Official Synonym Symbols: H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1
• NCBI Protein Information: guanine nucleotide-binding protein subunit beta-2-like 1; cell proliferation-inducing gene 21 protein; guanine nucleotide binding protein beta polypeptide 2-like 1; guanine nucleotide-binding protein subunit beta-like protein 12.3; human lung cancer oncogene 7 protein; protein homologous to chicken B complex protein, guanine nucleotide binding; receptor for activated C kinase 1; receptor of activated protein kinase C 1
• UniProt Protein Name: Guanine nucleotide-binding protein subunit beta-2-like 1
• UniProt Gene Name: GNB2L1
• UniProt Synonym Gene Names: HLC-7; RACK1
• UniProt Entry Name: GBLP_HUMAN

Uniprot Description

RACK1: a G-beta like protein containing 7 WD domains. A presumptive scaffold protein, linking protein kinase C to its substrates. Binds inositol 1,4,5-trisphosphate receptors and regulates Ca2+ release by enhancing inositol 1,4,5-trisphosphate receptor binding affinity for inositol 1,4,5-trisphosphate. An insulin-like growth factor 1 receptor-interacting protein that can regulate IGF-1-mediated Akt activation and protection from cell death.

Protein type: Motility/polarity/chemotaxis; G protein, heterotrimeric; Nuclear receptor co-regulator; G protein; G protein, heterotrimeric beta; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5q35.3

Cellular Component: small ribosomal subunit; cytoskeleton; cell soma; mitochondrion; perinuclear region of cytoplasm; dendrite; cytoplasm; perikaryon; midbody; cytosol; nucleus; phagocytic cup

Molecular Function: protein tyrosine kinase inhibitor activity; protein binding; enzyme binding; protein homodimerization activity; protein kinase C binding; SH2 domain binding; caspase activator activity; protein complex scaffold; receptor tyrosine kinase binding; protein phosphatase binding; ion channel inhibitor activity; receptor binding

Biological Process: caspase activation; negative regulation of phagocytosis; negative regulation of Wnt receptor signaling pathway; negative regulation of protein kinase B signaling cascade; viral reproduction; positive regulation of apoptosis; regulation of cell cycle; positive regulation of protein homooligomerization; rhythmic process; gastrulation; cell cycle; osteoblast differentiation; regulation of protein localization; positive regulation of mitochondrial depolarization; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of translation; positive regulation of cAMP catabolic process; positive regulation of cyclic-nucleotide phosphodiesterase activity; negative regulation of cell growth; positive regulation of protein amino acid phosphorylation; regulation of cell division; positive regulation of GTPase activity; positive regulation of cell migration