Bovine guanine nucleotide binding protein (G protein) , alpha inhibiting activity polypeptide 1 ELISA Kit | GNAI1 elisa kit

Bovine Guanine nucleotide-binding protein G, GNAI1 ELISA Kit

Cat. Num. AAA9334071

• Reactivity: Bovine
• Synonyms: guanine nucleotide binding protein (G protein); alpha inhibiting activity polypeptide 1; Bovine Guanine nucleotide-binding protein G; GNAI1 ELISA Kit; Bovine Guanine nucleotide-binding protein G (GNAI1) ELISA kit; Gi; Gi1 protein alpha subunit; GNAI1 elisa kit

• Reactivity: Bovine

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 27805887
• NCBI GeneID: 281790
• NCBI Accession #: NP_776749.1
• NCBI GenBank Nucleotide #: NM_174324.2
• UniProt Accession #: P63097; P04898; P11015; P31871; Q2KJC0
• Molecular Weight: 40,361 Da
• NCBI Official Full Name: guanine nucleotide-binding protein G(i) subunit alpha-1
• NCBI Official Synonym Full Names: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1<
• NCBI Official Symbol: GNAI1
• NCBI Protein Information: guanine nucleotide-binding protein G(i) subunit alpha-1; guanine nucleotide-binding protein G(i) subunit alpha-1; adenylate cyclase-inhibiting G alpha protein; guanine nucleotide-binding protein G(i), alpha-1 subunit
• UniProt Protein Name: Guanine nucleotide-binding protein G(i) subunit alpha-1
• UniProt Gene Name: GNAI1
• UniProt Entry Name: GNAI1_BOVIN

Uniprot Description

G-alpha i1: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division. Interacts with GPSM1. Interacts with RGS12. Interacts (via active GTP- or inactive GDP-bound forms) with RGS14 (via RGS and GoLoco domains); the interaction occurs in the centrosomes. Interacts (GDP-bound form) with RIC8A (via C-terminus). Interacts with DRD2. G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Belongs to the G-alpha family. G(i/o/t/z) subfamily.

Protein type: G protein, heterotrimeric alpha G((i/o/t/z)); G protein, heterotrimeric; G protein

Chromosomal Location of Human Ortholog: 7q21

Cellular Component: centrosome; lysosomal membrane; cytoplasm; plasma membrane; heterotrimeric G-protein complex; midbody; nucleus

Molecular Function: GTPase activity; protein binding; signal transducer activity; GTP binding; metal ion binding; G-protein beta/gamma-subunit binding; metabotropic serotonin receptor binding

Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein coupled receptor protein signaling pathway; synaptic transmission; platelet activation; response to peptide hormone stimulus; cell division; metabolic process; G-protein signaling, adenylate cyclase inhibiting pathway; cell cycle; blood coagulation