Human guanine nucleotide binding protein (G protein) , alpha 13 ELISA Kit | GNA13 elisa kit

Human Guanine nucleotide-binding protein subunit alpha-13, GNA13 ELISA Kit

Cat. Num. AAA9340640

• Gene Names: GNA13; G13
• Reactivity: Human
• Synonyms: guanine nucleotide binding protein (G protein); alpha 13; Human Guanine nucleotide-binding protein subunit alpha-13; GNA13 ELISA Kit; Human Guanine nucleotide-binding protein subunit alpha-13 (GNA13) ELISA kit; G13; MGC46138; ; GNA13 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples.
• Assay Type: Sandwich (Quantitative)
• Detection Range: 31.2 pg/ml - 1000 pg/ml.
• Sensitivity: 5.0 pg/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for GNA13 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of GNA13 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

References

Bone Homeostasis as a Multifaceted Puzzle: From WNT Ligands to Metal-ion Transporters. G. Hendrickx (2017)

NCBI and Uniprot Product Information

• NCBI GI #: 540344574
• NCBI GeneID: 10672
• NCBI Accession #: NP_001269354.1
• NCBI GenBank Nucleotide #: NM_001282425.1
• UniProt Accession #: Q14344; Q8TD70; B2R977; B7Z7R0; F5H1G8
• Molecular Weight: 44,050 Da
• NCBI Official Full Name: guanine nucleotide-binding protein subunit alpha-13 isoform 2
• NCBI Official Synonym Full Names: guanine nucleotide binding protein (G protein), alpha 13
• NCBI Official Symbol: GNA13
• NCBI Official Synonym Symbols: G13
• NCBI Protein Information: guanine nucleotide-binding protein subunit alpha-13; g alpha-13; G-protein subunit alpha-13
• UniProt Protein Name: Guanine nucleotide-binding protein subunit alpha-13
• Protein Family: Guanine nucleotide-binding protein
• UniProt Gene Name: GNA13
• UniProt Synonym Gene Names: G alpha-13; G-protein subunit alpha-13
• UniProt Entry Name: GNA13_HUMAN

Uniprot Description

G-alpha 13: a guanine nucleotide-binding protein of the G12 class of G-alpha proteins. Activates Rho. Protein kinase A blocks Rho activation by phosphorylation of G-alpha(13). Heterotrimeric G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Regulates cytoplasmic as well as nuclear signaling events such as activation of the Jun N-terminal kinase signaling module, Na+/H+ exchangers, focal adhesion assemblies, and transcriptional activation of specific primary response genes.

Protein type: G protein, heterotrimeric; G protein, heterotrimeric alpha G(12); G protein

Chromosomal Location of Human Ortholog: 17q24.3

Cellular Component: focal adhesion; membrane; brush border membrane; plasma membrane; melanosome; heterotrimeric G-protein complex; nucleus

Molecular Function: GTPase activity; signal transducer activity; protein binding; GTP binding; metal ion binding; G-protein beta/gamma-subunit binding; type 1 angiotensin receptor binding; D5 dopamine receptor binding

Biological Process: platelet activation; phospholipase D activation; metabolic process; in utero embryonic development; signal transduction; regulation of cell migration; G-protein signaling, adenylate cyclase activating pathway; Rho protein signal transduction; patterning of blood vessels; regulation of cell shape; elevation of cytosolic calcium ion concentration; cell differentiation; blood coagulation; cell motility