GMF beta recombinant protein
GMF beta protein
Gene Names
GMFB; GMF
Purity
> 98% pureGMF beta protein was purified using a a proprietary chromatographic technique.
Synonyms
GMF beta; GMF beta protein; GMF protein; Glia maturation factor beta protein; GMFB protein; GMF- beta protein; GMF-B protein; GMF beta recombinant protein
Host
Human
Purity/Purification
> 98% pure
GMF beta protein was purified using a a proprietary chromatographic technique.
GMF beta protein was purified using a a proprietary chromatographic technique.
Form/Format
Supplied in lyophilized form after dialysis against 20 mM PBS pH 7.4 and 130 mM NaCl
Sequence Length
142
Protein Type
Recombinant
Biological Significance
Glia Maturation Factor- beta is a 17 kDa protein nerve growth factor identified as a growth and differentiation factor in the vertebrate brain.Glia Maturation Factor- beta stimulates differentiation of normal neurons as well as glial cells. GMFB inhibits the proliferation of the N-18 neuroblastoma line and the C6 glioma line while promoting their phenotypic expression.GMF- beta enhances the phenotypic expression of glia & neurons thus inhibits the proliferation of their respective tumors when added to cell culture. Cell-surface GMF- beta acts on the target cells at close range when cells are in direct contact. GMF- beta is produced by thymic epithelial cells and plays an important role in T cell development in favor of CD4+ T cells.
Expression System
E Coli
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for GMF beta recombinant protein
Purified recombinant Human GMF beta protein
Product Categories/Family for GMF beta recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17.0 kDa
NCBI Official Full Name
glia maturation factor beta
NCBI Official Synonym Full Names
glia maturation factor, beta
NCBI Official Symbol
GMFB
NCBI Official Synonym Symbols
GMF
NCBI Protein Information
glia maturation factor beta
UniProt Protein Name
Glia maturation factor beta
UniProt Gene Name
GMFB
UniProt Synonym Gene Names
GMF-beta
UniProt Entry Name
GMFB_HUMAN
Uniprot Description
GMF-beta: This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. Belongs to the actin-binding proteins ADF family. GMF subfamily.
Protein type: Motility/polarity/chemotaxis; Inhibitor; Actin-binding
Chromosomal Location of Human Ortholog: 14q22.2
Cellular Component: intracellular
Molecular Function: signal transducer activity; growth factor activity; protein kinase inhibitor activity; enzyme activator activity; actin binding
Biological Process: positive regulation of catalytic activity; nervous system development; negative regulation of protein kinase activity; locomotory behavior; learning; signal transduction; protein amino acid phosphorylation
Research Articles on GMF beta
Similar Products
Product Notes
The GMF beta gmfb (Catalog #AAA5304255) is a Recombinant Protein produced from Human and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "GMF beta, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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