Glutathione S-transferase omega 1, 140D alanine-to-aspartate variant Recombinant Protein
Glutathione S-transferase omega 1, 140D alanine-to-aspartate variant, Recombinant, Human (GSTTL p28, Glutathione transferase omega, Gutathione-S-transferase like, Monomethyl Arsenous Reductase)
Purified. 95% by SDS-PAGE.
Purified. 95% by SDS-PAGE.
GSTO1 is a member of the theta class glutathione S- transferase-like (GSTTL) protein family. GSTO1 is expressed in a wide range of human tissues and exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities and also catalyzes the reduction of monomethylarsonate, an intermediate in the pathway of arsenic biotransformation. GSTO1 protects from oxidative stress, a risk factor for Alzheimer disease, vascular dementia and stroke. Several polymorphisms in the coding regions of the human GSTO1 have been identified. A polymorphism causing an alanine-to-aspartate (A140D) substitution in amino acid 140 produces a variant with lowered enzyme activities in the arsenic biotransformation.
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Product Notes
The Glutathione S-transferase omega 1, 140D alanine-to-aspartate variant (Catalog #AAA636822) is a Recombinant Protein produced from Human, Recombinant, E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Glutathione S-transferase omega 1, 140D alanine-to-aspartate variant can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Suitable for use in ELISA.,, Recommended Dilution:, Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the Glutathione S-transferase omega 1, 140D alanine-to-aspartate variant for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glutathione S-transferase omega 1, 140D alanine-to-aspartate variant, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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