Sensor histidine kinase GlrK (glrK) Recombinant Protein | glrK recombinant protein
Recombinant Escherichia coli Sensor histidine kinase GlrK (glrK)
NCBI and Uniprot Product Information
NCBI Description
Characterized in an EPEC strain, QseC activates transcription of qseEGF in response to the autoinducer-3 (AI-3)/epinephrine/norepinephrine interkingdom signaling system (Reading, 2007). [More information is available at EcoGene: EG13461]. Purified YfhK can transphosphorylate its cognate response regulator YfhA in vitro . [More information is available at EcoCyc: G7345].
Uniprot Description
Function: Member of the two-component regulatory system GlrR/GlrK that up-regulates transcription of the glmY sRNA when cells enter the stationary growth phase. Activates GlrR by phosphorylation. Ref.3 Ref.5
Catalytic activity: ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
Subcellular location: Cell inner membrane; Multi-pass membrane protein.
Post-translational modification: Autophosphorylated. Ref.3
Disruption phenotype: Mutants show decreased amounts of glmY. Ref.5
Miscellaneous: Not required for the regulation of the glmY-glmZ-glmS regulatory cascade by glucosamine-6-phosphate depletion.
Sequence similarities: Contains 1 histidine kinase domain.
Sequence caution: The sequence AAA79818.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
Research Articles on glrK
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Product Notes
The glrK glrk (Catalog #AAA1186814) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-475. The amino acid sequence is listed below: MKRWPVFPRS LRQLVMLAFL LILLPLLVLA WQAWQSLNAL SDQAALVNRT TLIDARRSEA MTNAALEMER SYRQYCVLDD PTLAKVYQSQ RKRYSEMLDA HAGVLPDDKL YQALRQDLHN LAQLQCNNSG PDAAAAARLE AFASANTEMV QATRTVVFSR GQQLQREIAE RGQYFGWQSL VLFLVSLVMV LLFTRMIIGP VKNIERMINR LGEGRSLGNS VSFSGPSELR SVGQRILWLS ERLSWLESQR HQFLRHLSHE LKTPLASMRE GTELLADQVV GPLTPEQKEV VSILDSSSRN LQKLIEQLLD YNRKQADSAV ELENVELAPL VETVVSAHSL PARAKMMHTD VDLKATACLA EPMLLMSVLD NLYSNAVHYG AESGNICLRS SLHGARVYID VINTGTPIPQ EERAMIFEPF FQGSHQRKGA VKGSGLGLSI ARDCIRRMQG ELYLVDESGQ DVCFRIELPS SKNTK. It is sometimes possible for the material contained within the vial of "Sensor histidine kinase GlrK (glrK), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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