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Glucagon-like peptide 1 receptor (Glp1r) Recombinant Protein | Glp1r recombinant protein

Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r), partial

Gene Names
Glp1r; Glip; RATGL1RCP
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Glucagon-like peptide 1 receptor (Glp1r); Recombinant Rat Glucagon-like peptide 1 receptor (Glp1r); partial; Short name: GLP-1 receptor Short name: GLP-1-R Short name: GLP-1R; Glp1r recombinant protein
Ordering
For Research Use Only!
Host
E. coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
Tris-based buffer, 50% glycerol
Sequence Positions
Partial. 22-135aa
Sequence
GPRPQGATVSLSETVQKWREYRHQCQRFLTEAPLLATGLFCNRTFDDYACWPDGPPGSFVNVSCPWYLPW
ASSVLQGHVYRFCTAEGIWLHKDNSSLPWRDLSECEESKQGERN
Tag Info
N-terminal 6xHis-tagged
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C, -80°C. The shelf life of lyophilized form is 12 months at -20°C, -80°C.
Store working aliquots at 4°C for up to one week.

Notes: Repeated freezing and thawing is not recommended.
Related Product Information for Glp1r recombinant protein
This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17.1 kDa
NCBI Official Full Name
glucagon-like peptide 1 receptor
NCBI Official Synonym Full Names
glucagon-like peptide 1 receptor
NCBI Official Symbol
Glp1r
NCBI Official Synonym Symbols
Glip; RATGL1RCP
NCBI Protein Information
glucagon-like peptide 1 receptor
UniProt Protein Name
Glucagon-like peptide 1 receptor
UniProt Gene Name
Glp1r
UniProt Synonym Gene Names
Glpr; GLP-1 receptor; GLP-1-R; GLP-1R

NCBI Description

induces insulin secretion; mediates neuroendocrine signaling of feeding behavior; mediates cardiovascular response and increased blood pressure [RGD, Feb 2006]

Uniprot Description

GLP1R: This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 20p12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; peptide hormone binding; peptide receptor activity; peptide receptor activity, G-protein coupled

Biological Process: associative learning; cAMP-mediated signaling; elevation of cytosolic calcium ion concentration; feeding behavior; G-protein signaling, adenylate cyclase activating pathway; hormone secretion; insulin secretion; learning and/or memory; memory; negative regulation of apoptosis; negative regulation of neuron apoptosis; neuropeptide signaling pathway; positive regulation of blood pressure; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of glucose import; positive regulation of heart contraction; positive regulation of insulin secretion; positive regulation of transcription from RNA polymerase II promoter; regulation of calcium ion transport; regulation of heart contraction; regulation of insulin secretion; release of sequestered calcium ion into cytosol; response to glucose stimulus

Research Articles on Glp1r

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Product Notes

The Glp1r glp1r (Catalog #AAA9424050) is a Recombinant Protein produced from E. coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Partial. 22-135aa. The amino acid sequence is listed below: GPRPQGATVS LSETVQKWRE YRHQCQRFLT EAPLLATGLF CNRTFDDYAC WPDGPPGSFV NVSCPWYLPW ASSVLQ GHVYRFCTAE GIWLHKDNSS LPWRDLSECE ESKQGERN. It is sometimes possible for the material contained within the vial of "Glucagon-like peptide 1 receptor (Glp1r), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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