Beta-galactosidase (Glb1) Recombinant Protein | Glb1 recombinant protein
Recombinant Mouse Beta-galactosidase (Glb1)
Gene Names
Glb1; Bge; Bgl; Bgs; Bgt; Bgl-e; Bgl-s; Bgl-t; AW125515; C130097A14Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Beta-galactosidase (Glb1); Recombinant Mouse Beta-galactosidase (Glb1); Glb1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
30-647aa; Full Length of Mature Protein
Sequence
QRTFKLDYSRDRFLKDGQPFRYISGSIHYFRIPRFYWEDRLLKMKMAGLNAIQMYVPWNFHEPQPGQYEFSGDRDVEHFIQLAHELGLLVILRPGPYICAEWDMGGLPAWLLEKQSIVLRSSDPDYLVAVDKWLAVLLPKMKPLLYQNGGPIITVQVENEYGSYFACDYDYLRFLVHRFRYHLGNDVILFTTDGASEKMLKCGTLQDLYATVDFGTGNNITQAFLVQRKFEPKGPLINSEFYTGWLDHWGKPHSTVKTKTLATSLYNLLARGANVNLYMFIGGTNFAYWNGANTPYEPQPTSYDYDAPLSEAGDLTKKYFALREVIQMFKEVPEGPIPPSTPKFAYGKVALRKFKTVAEALGILCPNGPVKSLYPLTFTQVKQYFGYVLYRTTLPQDCSNPKPIFSSPFNGVRDRAYVSVDGVPQGILDRNLMTALNIRGKAGATLDILVENMGRVNYGRFINDFKGLISNMTINSTVLTNWTVFPLNTEAMVRNHLWGREASDEGHLDGRSTSNSSDLILPTFYVGNFSIPSGIPDLPQDTFIQFPGWSKGQVWINGFNLGRYWPTMGPQKTLFVPRNILTTSAPNNITVLELEFAPCSEGTPELCTVEFVDTPVIS
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Glb1 recombinant protein
This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
73,121 Da
NCBI Official Full Name
beta-galactosidase preproprotein
NCBI Official Synonym Full Names
galactosidase, beta 1
NCBI Official Symbol
Glb1
NCBI Official Synonym Symbols
Bge; Bgl; Bgs; Bgt; Bgl-e; Bgl-s; Bgl-t; AW125515; C130097A14Rik
NCBI Protein Information
beta-galactosidase
UniProt Protein Name
Beta-galactosidase
Protein Family
UniProt Gene Name
Glb1
UniProt Synonym Gene Names
Bgl; Glb-1; Lactase
NCBI Description
This gene encodes a preproprotein that is proteolytically cleaved to yield a signal peptide and a proproptein that is subsequently processed to generate the active mature peptide. The encoded protein is a lysosomal enzyme that catalyzes the hydrolysis of terminal beta-D-galactose residues in various substrates like lactose, ganglioside GM1 and other glycoproteins. Mutations in the human gene are associated with GM1-gangliosidosis and Morquio B syndrome. Disruption of the mouse gene mirrors the symptoms of human gangliosidosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.
Research Articles on Glb1
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Product Notes
The Glb1 glb1 (Catalog #AAA950953) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 30-647aa; Full Length of Mature Protein. The amino acid sequence is listed below: QRTFKLDYSR DRFLKDGQPF RYISGSIHYF RIPRFYWEDR LLKMKMAGLN AIQMYVPWNF HEPQPGQYEF SGDRDVEHFI QLAHELGLLV ILRPGPYICA EWDMGGLPAW LLEKQSIVLR SSDPDYLVAV DKWLAVLLPK MKPLLYQNGG PIITVQVENE YGSYFACDYD YLRFLVHRFR YHLGNDVILF TTDGASEKML KCGTLQDLYA TVDFGTGNNI TQAFLVQRKF EPKGPLINSE FYTGWLDHWG KPHSTVKTKT LATSLYNLLA RGANVNLYMF IGGTNFAYWN GANTPYEPQP TSYDYDAPLS EAGDLTKKYF ALREVIQMFK EVPEGPIPPS TPKFAYGKVA LRKFKTVAEA LGILCPNGPV KSLYPLTFTQ VKQYFGYVLY RTTLPQDCSN PKPIFSSPFN GVRDRAYVSV DGVPQGILDR NLMTALNIRG KAGATLDILV ENMGRVNYGR FINDFKGLIS NMTINSTVLT NWTVFPLNTE AMVRNHLWGR EASDEGHLDG RSTSNSSDLI LPTFYVGNFS IPSGIPDLPQ DTFIQFPGWS KGQVWINGFN LGRYWPTMGP QKTLFVPRNI LTTSAPNNIT VLELEFAPCS EGTPELCTVE FVDTPVIS . It is sometimes possible for the material contained within the vial of "Beta-galactosidase (Glb1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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