IHC (Immunohiostchemistry)
(Immunohistochemistry of caspase-14 in human liver tissue with caspase-14 antibody at 2.5 μg/mL.)
Rabbit Caspase-14 Polyclonal Antibody | anti-Casp14 antibody
Caspase-14 Antibody
Gene Names
Casp14; MICE; mini-ICE
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Caspase-14 Antibody is affinity chromatography purified via peptide column.
Synonyms
Caspase-14, Antibody; Caspase-14 Antibody; Caspase-14; MICE; mini-ICE; Mini-ICE; CASP-14; caspase 14; anti-Casp14 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caspase-14 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Sequence Length
257
Applicable Applications for anti-Casp14 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
Caspase-14 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human caspase-14.
Buffer
Caspase-14 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Antibody can be stored at 4 degree C up to one year. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of caspase-14 in human liver tissue with caspase-14 antibody at 2.5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of caspase-14 in human liver tissue with caspase-14 antibody at 2.5 μg/mL.)
WB (Western Blot)
(Western blot analysis of caspase-14 in Jurkat cell lysate in the (A) absence or (B) presence of blocking peptide with caspase-14 antibody at 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of caspase-14 in Jurkat cell lysate in the (A) absence or (B) presence of blocking peptide with caspase-14 antibody at 1 μg/mL.)
Related Product Information for anti-Casp14 antibody
Caspase-14 Antibody: Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Caspase-14 is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,224 Da
NCBI Official Full Name
caspase-14
NCBI Official Synonym Full Names
caspase 14
NCBI Official Symbol
Casp14
NCBI Official Synonym Symbols
MICE; mini-ICE
NCBI Protein Information
caspase-14; CASP-14
UniProt Protein Name
Caspase-14
UniProt Gene Name
Casp14
UniProt Synonym Gene Names
CASP-14; MICE
UniProt Entry Name
CASPE_MOUSE
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Product Notes
The Casp14 casp14 (Catalog #AAA40241) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Caspase-14 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Caspase-14 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Casp14 casp14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Caspase-14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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