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Rabbit Growth hormone receptor ELISA Kit | GHR elisa kit

Rabbit Growth hormone receptor (GHR) ELISA Kit

Reactivity
Rabbit
Synonyms
Growth hormone receptor; Rabbit Growth hormone receptor (GHR) ELISA Kit; GHBP; growth hormone binding protein|serum binding protein|somatotropin receptor; GHR elisa kit
Ordering
For Research Use Only!
Reactivity
Rabbit
Specificity
This assay has high sensitivity and excellent specificity for detection of Rabbit GHR. No significant cross-reactivity or interference between Rabbit GHR and analogues was observed.
Sequence Length
638
Samples
Serum, Plasma, Other biological fluids
Assay Type
Sandwich
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for GHR elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate GHR in samples. An antibody specific for GHR has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyGHR present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for GHR is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of GHR bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
71,077 Da
NCBI Official Full Name
growth hormone receptor
NCBI Official Symbol
GHR
NCBI Protein Information
growth hormone receptor
UniProt Protein Name
Growth hormone receptor
Protein Family
UniProt Gene Name
GHR
UniProt Synonym Gene Names
GH receptor; GH-binding protein; GHBP

Uniprot Description

GH receptor: Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. Defects in GHR are a cause of Laron syndrome (LARS). A severe form of growth hormone insensitivity characterized by growth impairment, short stature, dysfunctional growth hormone receptor, and failure to generate insulin-like growth factor I in response to growth hormone. Defects in GHR may be a cause of idiopathic short stature autosomal (ISSA). Short stature is defined by a subnormal rate of growth. Belongs to the type I cytokine receptor family. Type 1 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, cytokine

Research Articles on GHR

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Product Notes

The Rabbit GHR ghr (Catalog #AAA285270) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA285270 ELISA Kit recognizes Rabbit GHR. It is sometimes possible for the material contained within the vial of "Growth hormone receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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