ATPase GET3 (GET3) Recombinant Protein | GET3 recombinant protein
Recombinant Lodderomyces elongisporus ATPase GET3 (GET3)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
ATPase GET3 (GET3); Recombinant Lodderomyces elongisporus ATPase GET3 (GET3); ATPase GET3; EC=3.6.-.-; Arsenical pump-driving ATPase; Arsenite-stimulated ATPase; Golgi to ER traffic protein 3; Guided entry of tail-anchored proteins 3; GET3 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-349aa; full length protein
Sequence
MELDLEPTLK PLIEQDTLKW IFVGGKGGVG KTTTSSSIAV QLALQHPESE FLLISTDPAHNLSDAFCQKF GKEARKVEGL SNLSCMEIDP EAAMSDLQQQ AQQYNNDPND PLKSIMSDMTGSIPGIDEAL SFMEVLKHIK NQKVNENDSK DKISYRTIIF DTAPTGHTLR FLQLPSTLQKLLGKFQQLSG KLGPMMSMLG GGAGGQQDMF EKLNEVQKNV AEVNEQFTDP ELTTFVCVCISEFLSLYETE RMIQELMSYK MDVNSIVVNQ LLFADDDENP CLRCVSRWKM QKKYLDQMAELYEDYHLVKM PLLGTEIRGV ENLKKFSKFL MVPYDPKKDR GLITEMKEQ
Sequence Length
349
Species
Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,461 Da
NCBI Official Full Name
hypothetical protein LELG_01521
NCBI Official Symbol
LELG_01521
NCBI Protein Information
similar to ATPase; hypothetical protein
UniProt Protein Name
ATPase GET3
Protein Family
UniProt Gene Name
GET3
UniProt Entry Name
GET3_LODEL
Uniprot Description
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
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Product Notes
The GET3 get3 (Catalog #AAA1008552) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-349aa; full length protein. The amino acid sequence is listed below: MELDLEPTLK PLIEQDTLKW IFVGGKGGVG KTTTSSSIAV QLALQHPESE FLLISTDPAH NLSDAFCQKF GKEARKVEGL SNLSCMEIDP EAAMSDLQQQ AQQYNNDPND PLKSIMSDMT GSIPGIDEAL SFMEVLKHIK NQKVNENDSK DKISYRTIIF DTAPTGHTLR FLQLPSTLQK LLGKFQQLSG KLGPMMSMLG GGAGGQQDMF EKLNEVQKNV AEVNEQFTDP ELTTFVCVCI SEFLSLYETE RMIQELMSYK MDVNSIVVNQ LLFADDDENP CLRCVSRWKM QKKYLDQMAE LYEDYHLVKM PLLGTEIRGV ENLKKFSKFL MVPYDPKKDR GLITEMKEQ. It is sometimes possible for the material contained within the vial of "ATPase GET3 (GET3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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