Golgi to ER traffic protein 2 (GET2) Recombinant Protein | KLTH0A05126g recombinant protein
Recombinant Lachancea thermotolerans Golgi to ER traffic protein 2 (GET2)
NCBI and Uniprot Product Information
Uniprot Description
Function: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER
By similarity.
Subunit structure: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3
By similarity.
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein
By similarity. Golgi apparatus membrane; Multi-pass membrane protein
By similarity.
Sequence similarities: Belongs to the GET2 family.
Sequence caution: The sequence CAR21238.1 differs from that shown. Reason: Erroneous initiation.
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Product Notes
The KLTH0A05126g get2 (Catalog #AAA1043367) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-306. The amino acid sequence is listed below: MSEISDAEKR RILREKRQQK FNKGGASSRL AKITGQTENS FLSTESPLDS RESTYPAQET KAPAGNEDST KQMDELLAKA TSKTTSKASS PPGSAEQQNG NPELDLFAQI AKLQQNANNE TVSTDPSGTP DIFAQLMASM QQDEAKGGSP GATAQQPIDP AIVEAHNIAV NKLKSYTILV KWLFFLLPYL YYITHSARDP FQHNAVNYVL DRSNFFTVFT TFEIVALSVY YQLLMSAEKS HNVNTLDNNS KILKLVSMVP PGLVPIPNLR GKVAQALQYW DVVSMYLTDL CFAIVLAGLF QYYHSM. It is sometimes possible for the material contained within the vial of "Golgi to ER traffic protein 2 (GET2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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