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General Glutathione S-transferase Assay Kit

Glutathione S-transferase Microplate Assay Kit

Reactivity
General
Applications
Functional Assay
Synonyms
Glutathione S-transferase; Glutathione S-transferase Microplate Assay Kit; EC 2.5.1.18; Glutathione transferase; Glutathione S-alkyltransferase; Glutathione S-aralkyltransferase; Glutathione S-aryltransferase; S-(hydroxyalkyl)glutathione lyase; Glutathione S-transferase assay kit
Ordering
For Research Use Only!
Reactivity
General
Applicable Applications for Glutathione S-transferase assay kit
Functional Assay
Samples
Urine, serum, plasma, tissue extracts, cell lysate, cell culture media and other biological fluids samples
Preparation and Storage
Shipped and store at 4 degree C for 6 months.
Related Product Information for Glutathione S-transferase assay kit
Background/Introduction: Glutathione S-transferases (GSTs) are a group of enzymes important in the detoxification of many xenobiotics in mammals. The enzymes protect cells against toxicants by conjugating the thiol group of the glutathione to electrophilic xenobiotics, and thereby defend cells against the mutagenic, carcinogenic, and toxic effects of the compounds. GST activity is present in plants, insects, yeast, bacteria, and most mammalian tissues especially in the liver, which plays a key role in detoxification. The Glutathione S-transferase Microplate Assay Kit is based upon the GST-catalyzed reaction between GSH and the GST substrate, CDNB (1-chloro-2,4-dinitrobenzene, which has the broadest range of isozyme detectability. Under certain conditions, the interaction between glutathione and CDNB is totally dependent on the presence of active GST. The GST-catalyzed formation of GS-DNB produces a dinitrophenyl thioether which can be detected by spectrophotometer at 340 nm.

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Product Notes

The General Glutathione S-transferase (Catalog #AAA8243172) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8243172 Assay Kit recognizes General Glutathione S-transferase. AAA Biotech's Glutathione S-transferase can be used in a range of immunoassay formats including, but not limited to, Functional Assay. Researchers should empirically determine the suitability of the Glutathione S-transferase for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glutathione S-transferase, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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