Human Growth Differentiation Factor 7 ELISA Kit | GDF7 elisa kit

Human Growth Differentiation Factor 7 ELISA Kit

Cat. Num. AAA41359

• Gene Names: GDF7; BMP12
• Reactivity: Human
• Synonyms: Growth Differentiation Factor 7; Human Growth Differentiation Factor 7 ELISA Kit; GDF7 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between Human GDF7 and analogues was observed.

• Samples: Monkey Body Fluids And Tissue Homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 62.5pg/ml-2000pg/ml
• Sensitivity: 10pg/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for GDF7 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of GDF15 (hereafter termed "analyte") in undiluted original Monkey body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 61835232
• NCBI GeneID: 151449
• NCBI Accession #: NP_878248.2
• NCBI GenBank Nucleotide #: NM_182828.2
• UniProt Accession #: Q7Z4P5
• Molecular Weight: 46,950 Da
• NCBI Official Full Name: growth/differentiation factor 7 preproprotein
• NCBI Official Synonym Full Names: growth differentiation factor 7
• NCBI Official Symbol: GDF7
• NCBI Official Synonym Symbols: BMP12
• NCBI Protein Information: growth/differentiation factor 7; GDF-7
• UniProt Protein Name: Growth/differentiation factor 7
• Protein Family: Growth/differentiation factor
• UniProt Gene Name: GDF7
• UniProt Synonym Gene Names: GDF-7
• UniProt Entry Name: GDF7_HUMAN

NCBI Description

This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord. [provided by RefSeq, Jul 2008]

Uniprot Description

GDF7: May play an active role in the motor area of the primate neocortex. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted; Cytokine; Cell development/differentiation

Chromosomal Location of Human Ortholog: 2p24.1

Cellular Component: extracellular space

Molecular Function: protein binding; protein homodimerization activity; growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: axon guidance; cell fate commitment; positive regulation of transcription, DNA-dependent; activin receptor signaling pathway; roof plate formation; forebrain morphogenesis; regulation of apoptosis; BMP signaling pathway; branching morphogenesis of a tube; epithelial cell differentiation; regulation of MAPKKK cascade; midbrain development; spinal cord association neuron differentiation; gland morphogenesis; positive regulation of neuron differentiation; cell development; reproductive structure development; growth