Human Growth Differentiation Factor 2 ELISA Kit | GDF2 elisa kit

Human Growth Differentiation Factor 2 ELISA Kit

Cat. Num. AAA21947

• Gene Names: GDF2; BMP9; BMP-9
• Reactivity: Human
• Synonyms: Growth Differentiation Factor 2; Human Growth Differentiation Factor 2 ELISA Kit; GDF2 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between Human GDF2 and analogues was observed.

• Samples: Serum, Plasma, Tissue Homogenate, Feces, Urine and Body Fluids
• Assay Type: Sandwich
• Detection Range: 3.12 pg/ml – 100 pg/ml.
• Sensitivity: 1.0 pg/ml.
• Intended Uses: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate GDF2 concentrations in Human serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research, not for drug, household, therapeutic applications
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean x100]
• Preparation and Storage: Store all reagents at 2-8 degree C

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for GDF2 elisa kit

Introduction: ELISA is a simple and highly sensitive method of analysis that allows for simultaneous and rapid quantification of a large number of samples. The assay is based on the specific recognition of the target compound (analyte/antigen) by antibodies which bind to the compound. The antigen-antibody complex is detected and measured with the aid of an enzyme-labeled antibody or antigen. Upon addition of a non-colored reagent, the enzyme produces a color reaction where the color intensity is directly or inversely proportional to the concentration of the analyte in the sample. This quantitative Sandwich ELISA kit is in tended to determinate GDF2 concentrations in Human serum, plasma, tissue homogenates, feces, urine and body fluids, and it is only for research!

NCBI and Uniprot Product Information

• NCBI GI #: 7705308
• NCBI GeneID: 2658
• NCBI Accession #: NP_057288.1
• NCBI GenBank Nucleotide #: NM_016204.1
• UniProt Accession #: Q9UK05; Q5VSQ9; Q9Y571
• Molecular Weight: 47,320 Da
• NCBI Official Full Name: growth/differentiation factor 2
• NCBI Official Synonym Full Names: growth differentiation factor 2
• NCBI Official Symbol: GDF2
• NCBI Official Synonym Symbols: BMP9; BMP-9
• NCBI Protein Information: growth/differentiation factor 2; GDF-2; bone morphogenetic protein 9
• UniProt Protein Name: Growth/differentiation factor 2
• Protein Family: Growth/differentiation factor
• UniProt Gene Name: GDF2
• UniProt Synonym Gene Names: BMP9; GDF-2; BMP-9
• UniProt Entry Name: GDF2_HUMAN

NCBI Description

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. [provided by RefSeq, Jul 2008]

Uniprot Description

GDF2: Could be involved in bone formation. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q11.22

Cellular Component: extracellular space

Molecular Function: protein binding; growth factor activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: cellular iron ion homeostasis; positive regulation of transcription, DNA-dependent; activin receptor signaling pathway; regulation of apoptosis; positive regulation of interleukin-8 production; BMP signaling pathway; positive regulation of endothelial cell differentiation; angiogenesis; vasculogenesis; positive regulation of BMP signaling pathway; ossification; negative regulation of blood vessel endothelial cell migration; osteoblast differentiation; patterning of blood vessels; positive regulation of osteoblast differentiation; negative regulation of angiogenesis; positive regulation of angiogenesis; negative regulation of DNA replication; cartilage development; regulation of MAPKKK cascade; negative regulation of endothelial cell proliferation; blood vessel morphogenesis; positive regulation of transcription from RNA polymerase II promoter; positive regulation of endothelial cell proliferation; negative regulation of cell growth; cell development; growth

Disease: Telangiectasia, Hereditary Hemorrhagic, Type 5