Guanine nucleotide-binding protein subunit beta (GB1) Recombinant Protein | GB1 recombinant protein

Recombinant Arabidopsis thaliana Guanine nucleotide-binding protein subunit beta (GB1)

Cat. Num. AAA1093620

• Gene Names: AGB1; ARABIDOPSIS G-PROTEIN BETA SUBUNIT; ATAGB1; ELK4; ERECTA-LIKE 4; GTP binding protein beta 1; T4L20.40; T4L20_40
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Guanine nucleotide-binding protein subunit beta (GB1); Recombinant Arabidopsis thaliana Guanine nucleotide-binding protein subunit beta (GB1); GB1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-377, Full length protein
• Sequence: MSVSELKERHAVATETVNNLRDQLRQRRLQLLDTDVARYSAAQGRTRVSFGATDLVCCRTLQGHTGKVYSLDWTPERNRIVSASQDGRLIVWNALTSQKTHAIKLPCAWVMTCAFSPNGQSVACGGLDSVCSIFSLSSTADKDGTVPVSRMLTGHRGYVSCCQYVPNEDAHLITSSGDQTCILWDVTTGLKTSVFGGEFQSGHTADVLSVSISGSNPNWFISGSCDSTARLWDTRAASRAVRTFHGHEGDVNTVKFFPDGYRFGTGSDDGTCRLYDIRTGHQLQVYQPHGDGENGPVTSIAFSVSGRLLFAGYASNNTCYVWDTLLGEVVLDLGLQQDSHRNRISCLGLSADGSALCTGSWDSNLKIWAFGGHRRVI
• Sequence Length: 377

• Species: Arabidopsis thaliana (Mouse-ear cress)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 15236122
• NCBI GeneID: 829597
• NCBI Accession #: NP_195172.1
• NCBI GenBank Nucleotide #: NM_119611.5
• UniProt Accession #: P49177
• Molecular Weight: 41,006 Da
• NCBI Official Full Name: GTP binding protein beta 1
• NCBI Official Symbol: AGB1
• NCBI Official Synonym Symbols: ARABIDOPSIS G-PROTEIN BETA SUBUNIT; ATAGB1; ELK4; ERECTA-LIKE 4; GTP binding protein beta 1; T4L20.40; T4L20_40
• NCBI Protein Information: GTP binding protein beta 1
• UniProt Protein Name: Guanine nucleotide-binding protein subunit beta
• UniProt Gene Name: GB1

NCBI Description

Encodes the heterotrimeric G-protein beta subunit and is involved in organ shape. A significant fraction of the protein is found in the ER. Mutants carrying null alleles express similar fruit phenotypes, as seen in er plants, but differ from er in that the stem is only slightly shorter than that in the wild type, the pedicel is slightly longer than that in the wild type, and the leaves are rounder than those in er mutants. Gene is expressed in all tissues examined, with highest expression level found in siliques. It is involved in resistance to Plectosphaerella cucumerina. The predicted protein has two DWD motifs. It can bind to DDB1a in Y2H assays and may be involved in the formation of a CUL4-based E3 ubiquitin ligase. It seems to be involved in the calcium-mediated response to extracellular ATP.

Uniprot Description

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Together with GCR1 and GPA1, acts as a negative regulator of ABA during seed germination and early seedling development. The heterotrimeric G-protein controls defense responses to necrotrophic and vascular fungi probably by modulating cell wall-related genes expression (e.g. lower xylose content in cell walls); involved in resistance to fungal pathogens such as Alternaria brassicicola and Fusarium oxysporum. Modulates root architecture (e.g. lateral root formation). Acts with XGL3 in the positive regulation of root waving and root skewing. Involved in the asymmetric division of zygote and specification of apical and basal cell lineages (PubMed:27014878).