SDS-PAGE
Guanidinoacetate N-methyltransferase Recombinant Protein | Gamt recombinant protein
Recombinant Rat Guanidinoacetate N-methyltransferase
Gene Names
Gamt; GMT
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Guanidinoacetate N-methyltransferase; Recombinant Rat Guanidinoacetate N-methyltransferase; Gamt recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-236aa; Full Length
Sequence
MSSSAASPLFAPGEDCGPAWRAAPAAYDTSDTHLQILGKPVMERWETPYMHSLAAAAASRGGRVLEVGFGMAIAASRVQQAPIKEHWIIECNDGVFQRLQNWALKQPHKVVPLKGLWEEEAPTLPDGHFDGILYDTYPLSEETWHTHQFNFIKTHAFRLLKPGGILTYCNLTSWGELMKSKYTDITAMFEETQVPALLEAGFQRENICTEVMALVPPADCRYYAFPQMITPLVTKH
Sequence Length
236
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-PAGE
SDS-PAGE
References
Molecular cloning, sequence analysis, and expression in Escherichia coli of the cDNA for guanidinoacetate methyltransferase from rat liver.Ogawa H., Date T., Gomi T., Konishi K., Pitot H.C., Cantoni G.L., Fujioka M.Proc. Natl. Acad. Sci. U.S.A. 85:694-698(1988)
Nucleotide sequence of the rat guanidinoacetate methyltransferase gene.Ogawa H., Fujioka M.Nucleic Acids Res. 16:8715-8716(1988)
Recombinant rat guanidinoacetate methyltransferase
structure and function of the NH2-terminal region as deduced by limited proteolysis.Fujioka M., Takata Y., Gomi T.Arch. Biochem. Biophys. 285:181-186(1991)
Endogenous synthesis and transport of creatine in the rat brain
an in situ hybridization study.Braissant O., Henry H., Loup M., Eilers B., Bachmann C.Brain Res. Mol. Brain Res. 86:193-201(2001)
Creatine synthesis and transport during rat embryogenesis
spatiotemporal expression of AGAT, GAMT and CT1.Braissant O., Henry H., Villard A.M., Speer O., Wallimann T., Bachmann C.BMC Dev. Biol. 5:9-9(2005)
Crystal structure of guanidinoacetate methyltransferase from rat liver
a model structure of protein arginine methyltransferase.Komoto J., Huang Y., Takata Y., Yamada T., Konishi K., Ogawa H., Gomi T., Fujioka M., Takusagawa F.J. Mol. Biol. 320:223-235(2002)
Monoclinic guanidinoacetate methyltransferase and gadolinium ion-binding characteristics.Komoto J., Takata Y., Yamada T., Konishi K., Ogawa H., Gomi T., Fujioka M., Takusagawa F.Acta Crystallogr. D 59:1589-1596(2003)
Catalytic mechanism of guanidinoacetate methyltransferase
crystal structures of guanidinoacetate methyltransferase ternary complexes.Komoto J., Yamada T., Takata Y., Konishi K., Ogawa H., Gomi T., Fujioka M., Takusagawa F.Biochemistry 43:14385-14394(2004)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
30.4 kDa
NCBI Official Full Name
Guanidinoacetate N-methyltransferase
NCBI Official Synonym Full Names
guanidinoacetate N-methyltransferase
NCBI Official Symbol
Gamt
NCBI Official Synonym Symbols
GMT
NCBI Protein Information
guanidinoacetate N-methyltransferase
UniProt Protein Name
Guanidinoacetate N-methyltransferase
Protein Family
UniProt Gene Name
Gamt
UniProt Entry Name
GAMT_RAT
NCBI Description
catalyzes the last step of creatine biosynthesis [RGD, Feb 2006]
Uniprot Description
Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor. Important in nervous system development.
Research Articles on Gamt
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Product Notes
The Gamt gamt (Catalog #AAA949202) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-236aa; Full Length. The amino acid sequence is listed below: MSSSAASPLF APGEDCGPAW RAAPAAYDTS DTHLQILGKP VMERWETPYM HSLAAAAASR GGRVLEVGFG MAIAASRVQQ APIKEHWIIE CNDGVFQRLQ NWALKQPHKV VPLKGLWEEE APTLPDGHFD GILYDTYPLS EETWHTHQFN FIKTHAFRLL KPGGILTYCN LTSWGELMKS KYTDITAMFE ETQVPALLEA GFQRENICTE VMALVPPADC RYYAFPQMIT PLVTKH. It is sometimes possible for the material contained within the vial of "Guanidinoacetate N-methyltransferase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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