Putative PTS system glucosamine-specific EIICBA component (gamP) Recombinant Protein | nagP recombinant protein
Recombinant Bacillus subtilis Putative PTS system glucosamine-specific EIICBA component (gamP)
NCBI and Uniprot Product Information
Uniprot Description
Function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
By similarity. This system may be involved in glucosamine transport. Ref.4
Catalytic activity: Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine.Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate.
Subcellular location: Cell membrane; Multi-pass membrane protein
Potential.
Domain: The EIIC domain forms the PTS system translocation channel and contains the specific substrate-binding site.The EIIB domain is phosphorylated by phospho-EIIA on a cysteinyl or histidyl residue, depending on the transported sugar. Then, it transfers the phosphoryl group to the sugar substrate concomitantly with the sugar uptake processed by the EIIC domain.The EIIA domain is phosphorylated by phospho-HPr on a histidyl residue. Then, it transfers the phosphoryl group to the EIIB domain.
Sequence similarities: Contains 1 PTS EIIA type-1 domain.Contains 1 PTS EIIB type-1 domain.Contains 1 PTS EIIC type-1 domain.
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Product Notes
The nagP gamp (Catalog #AAA1070523) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-631. The amino acid sequence is listed below: MFKKAFQILQ QLGRALMTPV AVLPAAGLLL RFGDKDLLNI PIIKDAGGVV FDNLPLIFAV GVAIGLAGGE GVAGLAAVIG YLILTVTLDN MGKLLGLQPP YEGAEHLIDM GVFGGIIIGL LAAYLYKRFS SIELHPVLGF FSGKRFVPII TSVSSLVIGV IFSFVWPLIQ NGINAASSLI ADSTVGLFFY ATIYRLLIPF GLHHIFYTPF YFMMGEYTDP STGNTVTGDL TRFFAGDPTA GRFMMGDFPY MIFCLPAVAL AIIHTARPEK KKMISGVMIS AALTSMLTGI TEPVEFSFLF VAPVLYLINS ILAGVIFVVC DLFHVRHGYT FSGGGIDYVL NYGLSTNGWV VIPVGIVFAF IYYYLFRFAI LKWNLKTPGR ETDEDGQNEE KAPVAKDQLA FHVLQALGGQ QNIANLDACI TRLRVTVHQP SQVCKDELKR LGAVGVLEVN NNFQAIFGTK SDALKDDIKT IMAGGVPATA AALDTVTDKP LKPDSDETFI YPIKGETVSL GDVPDQVFSE KMMGEGFAII PSEGKVVAPA DGEIVSIFPT KHAIGFMSAG GTEILIHVGI DTVKLNGEGF EAHVTSGQAV KQGELLLTFD LNYIKQHAAS AITPVIFTNT SEEDLKHIQM K. It is sometimes possible for the material contained within the vial of "Putative PTS system glucosamine-specific EIICBA component (gamP), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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