Galanin Like Peptide Recombinant Protein | GALP recombinant protein

Recombinant Galanin Like Peptide (GALP)

Cat. Num. AAA2034226

• Reactivity: Rat
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >95%
• Synonyms: Galanin Like Peptide; Recombinant Galanin Like Peptide (GALP); GALP recombinant protein

• Host: E Coli
• Reactivity: Rat
• Purity/Purification: >95%
• Sequence Length: 116

• Applicable Applications for GALP recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Fragment: Gly29~Leu115
• Tag: Two N-terminal Tags, His-tag and T7-tag
• Expression System: Prokaryotic Expression
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 14916445
• NCBI GeneID: 85569
• NCBI Accession #: NP_149097.1
• NCBI GenBank Nucleotide #: NM_033106.3
• Molecular Weight: 13.3kDa
• NCBI Official Full Name: galanin-like peptide isoform 1
• NCBI Official Synonym Full Names: galanin like peptide
• NCBI Official Symbol: GALP
• NCBI Protein Information: galanin-like peptide
• UniProt Protein Name: Galanin-like peptide
• Protein Family: Galanin-like peptide
• UniProt Gene Name: GALP
• UniProt Entry Name: GALP_HUMAN

NCBI Description

This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, has vasoactive properties, displays antimicrobial activity against E. coli, and may serve as a marker for neuroblastic tumors.[provided by RefSeq, Nov 2014]

Uniprot Description

GALP: Hypothalamic neuropeptide which binds to the G-protein- coupled galanin receptors (GALR1, GALR2 and GALR3). Involved in a large number of putative physiological functions in CNS homeostatic processes, including the regulation of gonadotropin- releasing hormone secretion. Isoform 2 exhibits potent and dose- dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, a physiologic effects which does not appear to be mediated via GALR1 or GALR2. Belongs to the galanin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19q13.43

Cellular Component: extracellular region

Molecular Function: hormone activity

Biological Process: behavioral response to starvation; defense response to bacterium; neuropeptide signaling pathway; regulation of appetite; response to insulin stimulus