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Gallinacin-2 (GAL2) Recombinant Protein | GAL2 recombinant protein

Recombinant Chicken Gallinacin-2 (GAL2)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Gallinacin-2 (GAL2); Recombinant Chicken Gallinacin-2 (GAL2); Recombinant Gallinacin-2 (GAL2); Gallinacin-2; Gal-2; Beta-defensin 2; GAL2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
29-64aa; Cytoplasmic domain
Sequence
LF CKGGSCHFGG CPSHLIKVGS CFGFRSCCKWPWNA
Species
Gallus gallus (Chicken)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
7,142 Da
NCBI Official Full Name
gallinacin-2
NCBI Official Symbol
GAL2
NCBI Protein Information
gallinacin-2; Gal 2; gal-2; beta-defensin 2; antimicrobial peptide 2
UniProt Protein Name
Gallinacin-2
Protein Family
UniProt Gene Name
GAL2
UniProt Synonym Gene Names
Gal-2
UniProt Entry Name
GLL2_CHICK

Uniprot Description

Function: Potent antibacterial activity against the Gram-negative bacterium E.coli ML-35, and against the Gram-positive bacterium L.monocytogenes EGD. Lacks antifungal activity against C.albicans. Ref.5

Subcellular location: Secreted. Cytoplasmic granule.

Tissue specificity: Expressed in circulating heterophil granulocytes and bone marrow (at protein level). Strong expression in the bone marrow, lung and testis. Moderate expression in the bursa and intestine. Low expression in the cloaca, gall bladder, brain, pancreas, trachea, air sacs and spleen. Expressed in the vagina, ovarian stroma and the theca layer of the ovarian follicle, but not in the granulosa layer of the ovarian follicle. Ref.6 Ref.7 Ref.8 Ref.9

Developmental stage: Detected in the theca layer of the ovarian follicle in the white follicle (WF), F1, F3, F5, and postovulatory follicle stages. In the vagina expression is higher in laying hens than in non-laying hens, and is higher in older laying hens than in young laying hens. Ref.8 Ref.9

Induction: Not induced in the ovarian follicle by intravenous injection of LPS. Expression in cultured vaginal cells is increased by LPS and S.enteritidis. Ref.8 Ref.9

Sequence similarities: Belongs to the beta-defensin family.

Mass spectrometry: Molecular mass is 3916.0 Da from positions 29 - 64. Determined by ESI. Ref.5Molecular mass is 3916.1 Da from positions 29 - 64. Determined by MALDI. Ref.6

Research Articles on GAL2

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Product Notes

The GAL2 gal2 (Catalog #AAA1258233) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 29-64aa; Cytoplasmic domain. The amino acid sequence is listed below: LF CKGGSCHFGG CPSHLIKVGS CFGFRSCCKW PWNA. It is sometimes possible for the material contained within the vial of "Gallinacin-2 (GAL2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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