Galanin Recombinant Protein | GAL recombinant protein

Galanin Protein, Human, Recombinant (hFc Tag)

Cat. Num. AAA8120807

• Gene Names: GAL; GALN; GLNN; GMAP; GAL-GMAP
• Purity: >95% as determined by SDS-PAGE
• Synonyms: Galanin; Galanin Protein; Human; Recombinant (hFc Tag); Human Galanin/GAL Protein (Fc Tag); GAL-GMAP Protein; GALN Protein; GLNN Protein; GMAP Protein; galanin/GMAP prepropeptide; GAL recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >95% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Ser123

• Species: Human
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: Ala 20
• Tag: C-human IgG1-Fc
• Protein Construction: A DNA sequence encoding the human GAL (P22466)(Met1-Ser123) was expressed with the Fc region of human IgG1 at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

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Product Categories/Family for GAL recombinant protein

Neurotransmitter Associated Enzymes

NCBI and Uniprot Product Information

• NCBI GI #: 27804313
• NCBI GeneID: 51083
• NCBI Accession #: NP_057057.2
• NCBI GenBank Nucleotide #: NM_015973.3
• UniProt Accession #: P22466; Q14413
• Molecular Weight: 13,302 Da
• NCBI Official Full Name: galanin peptides preproprotein
• NCBI Official Synonym Full Names: galanin/GMAP prepropeptide
• NCBI Official Symbol: GAL
• NCBI Official Synonym Symbols: GALN; GLNN; GMAP; GAL-GMAP
• NCBI Protein Information: galanin peptides; galanin prepropeptide; galanin-related peptide; galanin-message-associated peptide
• UniProt Protein Name: Galanin peptides
• Protein Family: Galanin
• UniProt Gene Name: GAL
• UniProt Synonym Gene Names: GAL1; GALN; GLNN; GMAP
• UniProt Entry Name: GALA_HUMAN

NCBI Description

Galanin is small neuropeptide that functions as a cellular messenger within the central and peripheral nervous systems, modulating diverse physiologic functions (Mechenthaler, 2008 [PubMed 18500643]).[supplied by OMIM, Jan 2009]

Uniprot Description

Galanin: Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion. Belongs to the galanin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 11q13.3

Cellular Component: Golgi apparatus; extracellular space; cell soma; extracellular region; secretory granule

Molecular Function: type 3 galanin receptor binding; neuropeptide hormone activity; protein binding; type 2 galanin receptor binding; type 1 galanin receptor binding

Biological Process: response to drug; nervous system development; positive regulation of cortisol secretion; positive regulation of apoptosis; positive regulation of catagen; negative regulation of lymphocyte proliferation; response to insulin stimulus; cAMP-mediated signaling; response to estrogen stimulus; insulin secretion; neuropeptide signaling pathway; regulation of glucocorticoid metabolic process; positive regulation of transcription from RNA polymerase II promoter; feeding behavior; inflammatory response

Disease: Epilepsy, Familial Temporal Lobe, 8