Ras GTPase-activating protein-binding protein 1 (G3bp1) Recombinant Protein | G3bp1 recombinant protein

Recombinant Mouse Ras GTPase-activating protein-binding protein 1 (G3bp1)

Cat. Num. AAA950484

• Gene Names: G3bp1; G3bp; C87777; AI849976; mKIAA4115; B430204O07
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Ras GTPase-activating protein-binding protein 1 (G3bp1); Recombinant Mouse Ras GTPase-activating protein-binding protein 1 (G3bp1); G3bp1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 2-465, Full length protein
• Sequence: VMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYAHGGLDSNGKPADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQTVSNDLEEHLEEPVVEPEPEPEPEPEPEPVSDIQEDKPEAALEEAAPDDVQKSTSPAPADVAPAQEDLRTFSWASVTSKNLPPSGAVPVTGTPPHVVKVPASQPRPESKPDSQIPPQRPQRDQRVREQRINIPPQRGPRPIREAGEPGDVEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGAVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGPSGGMRGPPRGGMVQKPGFGVGRGITTPRQ
• Sequence Length: 464

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for G3bp1 recombinant protein

This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3 -tailed substrates and can also unwind partial RNA
DNA and RNA
RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

NCBI and Uniprot Product Information

• NCBI GI #: 7305075
• NCBI GeneID: 27041
• NCBI Accession #: NP_038744.1
• NCBI GenBank Nucleotide #: NM_013716.2
• UniProt Accession #: P97855
• Molecular Weight: 51,829 Da
• NCBI Official Full Name: ras GTPase-activating protein-binding protein 1
• NCBI Official Synonym Full Names: GTPase activating protein (SH3 domain) binding protein 1
• NCBI Official Symbol: G3bp1
• NCBI Official Synonym Symbols: G3bp; C87777; AI849976; mKIAA4115; B430204O07
• NCBI Protein Information: ras GTPase-activating protein-binding protein 1
• UniProt Protein Name: Ras GTPase-activating protein-binding protein 1
• Protein Family: Ras GTPase-activating protein-binding protein
• UniProt Gene Name: G3bp1
• UniProt Synonym Gene Names: G3bp; G3BP-1

Uniprot Description

May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.